Arndt–Eistert reaction

Arndt-Eistert reaction
Named after Fritz Arndt, Bernd Eistert
Reaction type Homologation reaction
Identifiers
Organic Chemistry Portal arndt-eistert-synthesis
RSC ontology ID RXNO:0000063

In organic chemistry, the Arndt–Eistert reaction is the conversion of a carboxylic acid to its homologue. It is named for the German chemists Fritz Arndt (1885–1969) and Bernd Eistert (1902–1978). The method entails treating an acid chloride with diazomethane. It is a popular method of producing β-amino acids from α-amino acids.[1]

  1. ^ Ye, T.; McKervey, M. A. (1994). "Organic Synthesis with α-Diazo Carbonyl Compounds". Chem. Rev. 94 (4): 1091–1160. doi:10.1021/cr00028a010.
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