Benzophenone

Benzophenone
Names
	Preferred IUPAC name Diphenylmethanone
	Other names Benzophenone ; Diphenyl ketone; Benzoylbenzene; Benzoylphenyl
Identifiers
CAS Number	119-61-9 ;
3D model (JSmol)	Interactive image;
Beilstein Reference	1238185
ChEBI	CHEBI:41308 ;
ChEMBL	ChEMBL90039 ;
ChemSpider	2991 ;
DrugBank	DB01878 ;
ECHA InfoCard	100.003.943
EC Number	204-337-6;
Gmelin Reference	4256
KEGG	C06354 ;
PubChem CID	3102;
RTECS number	DI9950000;
UNII	701M4TTV9O ;
UN number	1224
CompTox Dashboard (EPA)	DTXSID0021961 ;
	InChI InChI=1S/C13H10O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H Key: RWCCWEUUXYIKHB-UHFFFAOYSA-N ; InChI=1/C13H10O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H Key: RWCCWEUUXYIKHB-UHFFFAOYAX;
	SMILES O=C(c1ccccc1)c2ccccc2;
Properties
Chemical formula	C13H10O
Molar mass	182.222 g·mol−1
Appearance	White solid
Odor	Geranium-like
Density	1.11 g/cm3
Melting point	48.5 °C (119.3 °F; 321.6 K)
Boiling point	305.4 °C (581.7 °F; 578.5 K)
Solubility in water	Insoluble
Solubility in organic solvents	1 g/7.5 mL in ethanol; 1 g/6 mL in diethyl ether. Alkanes + tetrachloromethane: better with increasing tetrachloromethane content
Magnetic susceptibility (χ)	−109.6·10−6 cm3/mol
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Harmful (XN)
	GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H373, H411
Precautionary statements	P260, P273, P314, P391, P501
NFPA 704 (fire diamond)	1 1 0
Flash point	110 °C (230 °F; 383 K)
Safety data sheet (SDS)	External MSDS by Sigma-Aldritch
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Benzophenone is a naturally occurring organic compound with the formula (C₆H₅)₂CO, generally abbreviated Ph₂CO. Benzophenone has been found in some fungi, fruits and plants, including grapes.^[4] It is a white solid with a low melting point and rose-like odor^[5] that is soluble in organic solvents. Benzophenone is the simplest diaromatic ketone. It is a widely used building block in organic chemistry, being the parent diarylketone.

^ ^a ^b "Front Matter". Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. pp. 723–724, 726. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.
^ ^a ^b ^c ^d ^e ^f ^g Merck Index (11th ed.). p. 1108.
^ Azizian, Saeid; Haydarpour, Afshin (November 2003). "Solubility of Benzophenone in Binary Alkane + Carbon Tetrachloride Solvent Mixtures". Journal of Chemical & Engineering Data. 48 (6): 1476–1478. doi:10.1021/je0340497.
^ Surana, Khemchand; Chaudhary, Bharatkumar; Diwaker, Monika; Sharma, Satyasheel (2018). "Benzophenone: a ubiquitous scaffold in medicinal chemistry". MedChemComm. 9 (11): 1803–1817. doi:10.1039/C8MD00300A. ISSN 2040-2503. PMC 6238883. PMID 30542530.
^ "Molecule of the Week Archive: Benzophenone". American Chemical Society. 11 March 2024. Retrieved 20 May 2024.

[iupac2013-1] "Front Matter". Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. pp. 723–724, 726. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.

[Merck-2] ^ ^a ^b ^c ^d ^e ^f ^g Merck Index (11th ed.). p. 1108.

[3] Azizian, Saeid; Haydarpour, Afshin (November 2003). "Solubility of Benzophenone in Binary Alkane + Carbon Tetrachloride Solvent Mixtures". Journal of Chemical & Engineering Data. 48 (6): 1476–1478. doi:10.1021/je0340497.

[4] Surana, Khemchand; Chaudhary, Bharatkumar; Diwaker, Monika; Sharma, Satyasheel (2018). "Benzophenone: a ubiquitous scaffold in medicinal chemistry". MedChemComm. 9 (11): 1803–1817. doi:10.1039/C8MD00300A. ISSN 2040-2503. PMC 6238883. PMID 30542530.

[acs-5] "Molecule of the Week Archive: Benzophenone". American Chemical Society. 11 March 2024. Retrieved 20 May 2024.

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