Markovnikov's rule

In organic chemistry, Markovnikov's rule or Markownikoff's rule describes the outcome of some addition reactions. The rule was formulated by Russian chemist Vladimir Markovnikov in 1870.[1][2][3]

  1. ^ W. Markownikoff (1870). "Ueber die Abhängigkeit der verschiedenen Vertretbarkeit des Radical wasserstoffs in den isomeren Buttersäuren" [On the dependence of the different substitutions of the radical hydrogen in the isomeric butyric acids]. Annalen der Chemie. 153 (1): 228–259. doi:10.1002/jlac.18701530204.
  2. ^ Hughes, Peter (2006). "Was Markovnikov's Rule an Inspired Guess?". Journal of Chemical Education. 83 (8): 1152. Bibcode:2006JChEd..83.1152H. doi:10.1021/ed083p1152.
  3. ^ Lewis, David E. (2021). "The Logic Behind Markovnikov's Rule: Was It an Inspired Guess? …No!". Angewandte Chemie International Edition. 60 (9): 4412–4421. doi:10.1002/anie.202008228. S2CID 230570680.