Oxygen-18
| General | |
|---|---|
| Symbol | 18O |
| Names | oxygen-18, Ω, Heavy oxygen |
| Protons (Z) | 8 |
| Neutrons (N) | 10 |
| Nuclide data | |
| Natural abundance | 0.2% |
| Half-life (t1/2) | stable |
| Isotope mass | 17.9991610 Da |
| Spin | 0 |
| Isotopes of oxygen Complete table of nuclides | |
Oxygen-18 (18
O, Ω[1]) is a natural, stable isotope of oxygen and one of the environmental isotopes.
18
O is an important precursor for the production of fluorodeoxyglucose (FDG) used in positron emission tomography (PET). Generally, in the radiopharmaceutical industry, enriched water (H
2Ω) is bombarded with hydrogen ions in either a cyclotron or linear accelerator, producing fluorine-18. This is then synthesized into FDG and injected into a patient. It can also be used to make an extremely heavy version of water when combined with tritium (hydrogen-3): 3
H
218
O or T
2Ω. This compound has a density almost 30% greater than that of natural water.[2]
The accurate measurements of 18
O rely on proper procedures of analysis, sample preparation and storage.[3]
- ^ Capilla, José E.; Arevalo, Javier Rodriguez; Castaño, Silvino Castaño; Teijeiro, María Fé Díaz; del Moral, Rut Sanchez; Diaz, Javier Heredia (September 19, 2012). "Mapping Oxygen-18 in Meteoric Precipitation over Peninsular Spain using Geostatistical Tools" (PDF). cedex.es. Valencia, Spain: Ninth Conference on Geostatistics for Environmental Applications. Retrieved May 8, 2017.
- ^ Pauling, Linus (1988). "12-7. Heavy Water". General Chemistry (3rd ed.). Dover. p. 438. ISBN 978-0-486-65622-9.
- ^ Tsang, Man-Yin; Yao, Weiqi; Tse, Kevin (2020). Kim, Il-Nam (ed.). "Oxidized silver cups can skew oxygen isotope results of small samples". Experimental Results. 1: e12. doi:10.1017/exp.2020.15. ISSN 2516-712X.