Transamination

Transamination is a chemical reaction that transfers an amino group.

In biochemistry, the processor occurs extensively during amino acid synthesis, catalyzed by transaminase or aminotransferases, and requires a ketoacid. α-ketoglutarate acts as the predominant amino-group acceptor and produces glutamate.

Aminoacid + α-ketoglutarate ↔ α-keto acid + glutamate

Glutamate's amino group, in turn, is transferred to oxaloacetate in a second transamination reaction yielding aspartate.

Glutamate + oxaloacetate ↔ α-ketoglutarate + aspartate
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