11-Nor-9-carboxy-THC

11-Nor-9-carboxy-THC
Clinical data
Pregnancy; category	Inconclusive;
Routes of; administration	Variable
Pharmacokinetic data
Bioavailability	Variable
Metabolism	Variable
Elimination half-life	5.2 to 6.2 days
Excretion	Variable
Identifiers
	IUPAC name 1-Hydroxy-6,6-dimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromene-9-carboxylic acid;
CAS Number	56354-06-4 ;
PubChem CID	107885;
ChemSpider	97019 ;
UNII	4TPC9E4A32;
ChEBI	CHEBI:167808;
CompTox Dashboard (EPA)	DTXSID8074788 ;
Chemical and physical data
Formula	C21H28O4
Molar mass	344.451 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCCc1cc(c2c(c1)OC(C3C2C=C(CC3)C(=O)O)(C)C)O;
	InChI InChI=1S/C21H28O4/c1-4-5-6-7-13-10-17(22)19-15-12-14(20(23)24)8-9-16(15)21(2,3)25-18(19)11-13/h10-12,15-16,22H,4-9H2,1-3H3,(H,23,24) ; Key:YOVRGSHRZRJTLZ-UHFFFAOYSA-N ;
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11-Nor-9-carboxy-Δ⁹-tetrahydrocannabinol (11-COOH-THC or THC-COOH), often referred to as 11-nor-9-carboxy-THC or THC-11-oic acid, is the main secondary metabolite of tetrahydrocannabinol (THC) which is formed in the body after cannabis is consumed.

^ Schwilke EW, Schwope DM, Karschner EL, Lowe RH, Darwin WD, Kelly DL, et al. (December 2009). "Delta9-tetrahydrocannabinol (THC), 11-hydroxy-THC, and 11-nor-9-carboxy-THC plasma pharmacokinetics during and after continuous high-dose oral THC". Clinical Chemistry. 55 (12): 2180–2189. doi:10.1373/clinchem.2008.122119. PMC 3196989. PMID 19833841.

[1] Schwilke EW, Schwope DM, Karschner EL, Lowe RH, Darwin WD, Kelly DL, et al. (December 2009). "Delta9-tetrahydrocannabinol (THC), 11-hydroxy-THC, and 11-nor-9-carboxy-THC plasma pharmacokinetics during and after continuous high-dose oral THC". Clinical Chemistry. 55 (12): 2180–2189. doi:10.1373/clinchem.2008.122119. PMC 3196989. PMID 19833841.

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