2-Aminoindane

2-Aminoindane
Clinical data
Other names	2-Indanylamine; 2-Indanamine, SU-8629.
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	DE: NpSG (Industrial and scientific use only); UK: Under Psychoactive Substances Act; In general: uncontrolled;
Identifiers
	IUPAC name 2,3-Dihydro-1H-inden-2-amine;
CAS Number	2975-41-9 ;
PubChem CID	76310;
ChemSpider	68787 ;
UNII	1P810SQ3EY;
CompTox Dashboard (EPA)	DTXSID40183902 ;
ECHA InfoCard	100.019.111
Chemical and physical data
Formula	C9H11N
Molar mass	133.194 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1C(CC2=CC=CC=C21)N;
	InChI InChI=1S/C9H11N/c10-9-5-7-3-1-2-4-8(7)6-9/h1-4,9H,5-6,10H2 ; Key:LMHHFZAXSANGGM-UHFFFAOYSA-N ;
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2-Aminoindane (2-AI) is an aminoindane and research chemical with applications in neurologic disorders and psychotherapy that has also been sold as a designer drug.^[2] It acts as a selective substrate for NET and DAT.^[3]^[4]

^ PHARMACOLOGY OF 2-AMINO-INDANE HYDROCHLORIDE (SU-8629): A POTENT NON-NARCOTIC ANALGESIC. Witkin, L.B. et al. The Journal of Pharmacology and Experimental Therapeutics, Volume 133, Issue 3, 400 - 408
^ Manier SK, Felske C, Eckstein N, Meyer MR (October 2019). "The metabolic fate of two new psychoactive substances - 2-aminoindane and N-methyl-2-aminoindane - studied in vitro and in vivo to support drug testing". Drug Testing and Analysis. 12 (1): 145–151. doi:10.1002/dta.2699. PMID 31667988.
^ Halberstadt AL, Brandt SD, Walther D, Baumann MH (March 2019). "2-adrenergic receptors". Psychopharmacology. 236 (3): 989–999. doi:10.1007/s00213-019-05207-1. PMC 6848746. PMID 30904940.
^ Simmler LD, Rickli A, Schramm Y, Hoener MC, Liechti ME (March 2014). "Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives" (PDF). Biochemical Pharmacology. 88 (2): 237–44. doi:10.1016/j.bcp.2014.01.024. PMID 24486525.

[1] PHARMACOLOGY OF 2-AMINO-INDANE HYDROCHLORIDE (SU-8629): A POTENT NON-NARCOTIC ANALGESIC. Witkin, L.B. et al. The Journal of Pharmacology and Experimental Therapeutics, Volume 133, Issue 3, 400 - 408

[2] Manier SK, Felske C, Eckstein N, Meyer MR (October 2019). "The metabolic fate of two new psychoactive substances - 2-aminoindane and N-methyl-2-aminoindane - studied in vitro and in vivo to support drug testing". Drug Testing and Analysis. 12 (1): 145–151. doi:10.1002/dta.2699. PMID 31667988.

[3] Halberstadt AL, Brandt SD, Walther D, Baumann MH (March 2019). "2-adrenergic receptors". Psychopharmacology. 236 (3): 989–999. doi:10.1007/s00213-019-05207-1. PMC 6848746. PMID 30904940.

[4] Simmler LD, Rickli A, Schramm Y, Hoener MC, Liechti ME (March 2014). "Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives" (PDF). Biochemical Pharmacology. 88 (2): 237–44. doi:10.1016/j.bcp.2014.01.024. PMID 24486525.

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