2C-TFM

2C-TFM
Clinical data
Other names	2C-CF3; 2,5-Dimethoxy-4-trifluoromethylphenethylamine; 4-Trifluoromethyl-2,5-dimethoxyphenethylamine
Routes of; administration	Oral
Drug class	Serotonin 5-HT2 receptor agonist; Serotonergic psychedelic; Hallucinogen
Pharmacokinetic data
Duration of action	≥5–10 hours
Identifiers
	IUPAC name 2-[2,5-dimethoxy-4-(trifluoromethyl)phenyl]ethan-1-amine;
CAS Number	159277-08-4 ;
PubChem CID	10399795;
ChemSpider	8575233 ;
UNII	16O4G6IKYL;
ChEMBL	ChEMBL136354 ;
CompTox Dashboard (EPA)	DTXSID70439308 ;
Chemical and physical data
Formula	C11H14F3NO2
Molar mass	249.233 g·mol−1
3D model (JSmol)	Interactive image;
Melting point	260 °C (500 °F) (hydrochloride)
	SMILES FC(F)(C1=C(OC)C=C(CCN)C(OC)=C1)F;
	InChI InChI=1S/C11H14F3NO2/c1-16-9-6-8(11(12,13)14)10(17-2)5-7(9)3-4-15/h5-6H,3-4,15H2,1-2H3 ; Key:LYXGNMLWYONZID-UHFFFAOYSA-N ;
	(verify)

2C-TFM, also known as 4-trifluoromethyl-2,5-dimethoxyphenethylamine, is a serotonin 5-HT₂ receptor agonist and psychedelic drug of the phenethylamine and 2C families.^[1]^[2] It has also been called 2C-CF₃, a name derived from the para-trifluoromethyl group it contains. The drug was first synthesized in the laboratory of David E. Nichols. Later, it was tried humans and its psychedelic effects were confirmed.^[1] 2C-TFM is the most potent psychedelic of the 2C psychedelics, with an active dosage of 3 to 6 mg orally.^[1]^[2]

^ ^a ^b ^c ^d Cite error: The named reference Trachsel2012 was invoked but never defined (see the help page).
^ ^a ^b ^c Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: von der Struktur zur Funktion [Phenethylamines: From Structure to Function]. Nachtschatten-Science (in German) (1 ed.). Solothurn: Nachtschatten-Verlag. ISBN 978-3-03788-700-4. OCLC 858805226.
^ Cite error: The named reference Nichols was invoked but never defined (see the help page).

[Trachsel2012-1] Cite error: The named reference Trachsel2012 was invoked but never defined (see the help page).

[TrachselLehmannEnzensperger2013-2] Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: von der Struktur zur Funktion [Phenethylamines: From Structure to Function]. Nachtschatten-Science (in German) (1 ed.). Solothurn: Nachtschatten-Verlag. ISBN 978-3-03788-700-4. OCLC 858805226.

[Nichols-3] Cite error: The named reference Nichols was invoked but never defined (see the help page).

[1]

[2]

[3]