3',4'-Methylenedioxy-α-pyrrolidinopropiophenone

MDPPP
Clinical data
Routes of; administration	By mouth, insufflation, vaporization, IV, rectal, sublingual
Legal status
Legal status	DE: Anlage I (Authorized scientific use only); UK: Class B;
Pharmacokinetic data
Metabolism	Hepatic
Excretion	Primarily urine (renal)
Identifiers
	IUPAC name (RS)-1-(3,4-methylenedioxyphenyl)-2-(1-pyrrolidinyl)-1-propanone;
CAS Number	783241-66-7;
PubChem CID	6430845;
ChemSpider	4936183;
UNII	83IP4LIH8E;
CompTox Dashboard (EPA)	DTXSID001024625 ;
Chemical and physical data
Formula	C14H17NO3
Molar mass	247.294 g·mol−1
3D model (JSmol)	Interactive image;
Chirality	Racemic mixture
	SMILES c3c1OCOc1ccc3C(=O)C(C)N2CCCC2;
	InChI InChI=1S/C14H17NO3/c1-10(15-6-2-3-7-15)14(16)11-4-5-12-13(8-11)18-9-17-12/h4-5,8,10H,2-3,6-7,9H2,1H3; Key:NIYQOTCYXGXMPI-UHFFFAOYSA-N;

3',4'-Methylenedioxy-α-pyrrolidinopropiophenone (MDPPP) is a stimulant designer drug. It was sold in Germany in the late 1990s and early 2000s as an ingredient in imitation ecstasy (MDMA) pills.^[3] It shares a similar chemical structure with α-PPP and MDPV,^[4]^[1]^[2] and has been shown to have reinforcing effects in rats.^[5]

^ ^a ^b Cite error: The named reference Staack was invoked but never defined (see the help page).
^ ^a ^b Cite error: The named reference Springer was invoked but never defined (see the help page).
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^ Gannon BM, Galindo KI, Mesmin MP, Sulima A, Rice KC, Collins GT (May 2018). "Relative reinforcing effects of second-generation synthetic cathinones: Acquisition of self-administration and fixed ratio dose-response curves in rats". Neuropharmacology. 134 (Pt A): 28–35. doi:10.1016/j.neuropharm.2017.08.018. PMC 5809320. PMID 28811192.

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[Springer-2] Cite error: The named reference Springer was invoked but never defined (see the help page).

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[Maurer-4] Cite error: The named reference Maurer was invoked but never defined (see the help page).

[5] Gannon BM, Galindo KI, Mesmin MP, Sulima A, Rice KC, Collins GT (May 2018). "Relative reinforcing effects of second-generation synthetic cathinones: Acquisition of self-administration and fixed ratio dose-response curves in rats". Neuropharmacology. 134 (Pt A): 28–35. doi:10.1016/j.neuropharm.2017.08.018. PMC 5809320. PMID 28811192.

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