Anti-neutrophil cytoplasmic antibody

Anti-neutrophil cytoplasmic antibodies (ANCAs) are a group of autoantibodies, mainly of the IgG type, against antigens in the cytoplasm of neutrophils (the most common type of white blood cell) and monocytes. They are detected as a blood test in a number of autoimmune disorders, but are particularly associated with systemic vasculitis, so called ANCA-associated vasculitides (AAV).[1]

  1. ^ Sharma P, Zonozi R, Geetha D (2024). "ANCA-Associated Vasculitis". Advances in Kidney Disease and Health. 31 (3): 194–205. doi:10.1053/j.akdh.2024.04.005. PMID 39004459.