Akkermansia muciniphila

Akkermansia muciniphila
Scanning electron micrograph of Akkermansia muciniphila[1]
Scientific classification
Domain:
Bacteria
Phylum:
Verrucomicrobiota
Class:
Verrucomicrobiae
Order:
Verrucomicrobiales
Family:
Akkermansiaceae
Genus:
Akkermansia
Species:
A. muciniphila
Binomial name
Akkermansia muciniphila
Derrien et al. 2004

Akkermansia muciniphila is a human intestinal symbiont, isolated from human feces.[2] It is a mucin-degrading bacterium belonging to the genus Akkermansia, discovered in 2004 by Muriel Derrien and Willem de Vos at Wageningen University of the Netherlands.[3][2]: 1474  It belongs to the phylum Verrucomicrobiota and its type strain is MucT (=ATCC BAA-835T =CIP 107961T).[2] It is under preliminary research for its potential beneficial associations with metabolic disorders.[4][5][6]

  1. ^ Zhang T, Li Q, Cheng L, et al. (November 2019). "Akkermansia muciniphila is a promising probiotic". Microbial Biotechnology. 12 (6): 1109–1125. doi:10.1111/1751-7915.13410. ISSN 1751-7915. PMC 6801136. PMID 31006995.
  2. ^ a b c Derrien M (2004). "Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium". International Journal of Systematic and Evolutionary Microbiology. 54 (5): 1469–1476. doi:10.1099/ijs.0.02873-0. PMID 15388697.
  3. ^ de Vos W (2017). "Microbe Profile: Akkermansia muciniphila: a conserved intestinal symbiont that acts as the gatekeeper of our mucosa". Microbiology. 1635 (5): 646–648. doi:10.1099/mic.0.000444. PMID 28530168.
  4. ^ Everard A, Belzer C, Geurts L, et al. (May 28, 2013). "Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity". Proceedings of the National Academy of Sciences of the United States of America. 110 (22): 9066–9071. Bibcode:2013PNAS..110.9066E. doi:10.1073/pnas.1219451110. PMC 3670398. PMID 23671105.{{cite journal}}: CS1 maint: overridden setting (link)
  5. ^ Dao MC, Everard A, Aron-Wisnewsky J, et al. (March 2016). "Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology". Gut. 65 (3): 426–436. doi:10.1136/gutjnl-2014-308778. hdl:10044/1/24139. PMID 26100928.{{cite journal}}: CS1 maint: overridden setting (link)
  6. ^ Luo Y, Lan C, Li H, et al. (October 17, 2022). "Rational consideration of Akkermansia muciniphila targeting intestinal health: advantages and challenges". npj Biofilms and Microbiomes. 8 (1): 81. doi:10.1038/s41522-022-00338-4. ISSN 2055-5008. PMC 9576740. PMID 36253412.{{cite journal}}: CS1 maint: overridden setting (link)
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