Ancrod
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| ECHA InfoCard | 100.029.927 |
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| Thrombin-like enzyme ancrod | |||||||
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| UniProt | P26324 | ||||||
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| Thrombin-like enzyme ancrod-2 | |||||||
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| UniProt | P47797 | ||||||
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Ancrod (current brand name: Viprinex) is a defibrinogenating agent derived from the venom of the Malayan pit viper. Defibrinogenating blood produces an anticoagulant effect. Ancrod is not approved or marketed in any country. It is a thrombin-like serine protease.[1]
- ^ Macheroux P, Seth O, Bollschweiler C, Schwarz M, Kurfürst M, Au LC, Ghisla S (March 2001). "L-amino-acid oxidase from the Malayan pit viper Calloselasma rhodostoma. Comparative sequence analysis and characterization of active and inactive forms of the enzyme". European Journal of Biochemistry. 268 (6): 1679–86. doi:10.1046/j.1432-1327.2001.02042.x. PMID 11248687.