Late-onset hypogonadism

Late-onset hypogonadism
SpecialtyEndocrinology 

Late-onset hypogonadism (LOH) or testosterone deficiency syndrome (TDS)[1][2] is a condition in older men characterized by measurably low testosterone levels and clinical symptoms mostly of a sexual nature, including decreased desire for mating, fewer spontaneous erections, and erectile dysfunction.[3] It is the result of a gradual drop in testosterone; a steady decline in testosterone levels of about 1% per year can happen and is well documented in both men and women.[4][5]

  1. ^ "Middle-age dread". 15 June 2013.
  2. ^ Jarlath Regan (26 May 2019). "Dr. Andrew Rynne". An Irishman Abroad (Podcast) (297 ed.). SoundCloud. Archived from the original on 27 May 2019. Retrieved 27 May 2019.
  3. ^ Dimopoulou, C; et al. (February 2016). "EMAS position statement: Testosterone replacement therapy in the aging male". Maturitas. 84: 94–9. doi:10.1016/j.maturitas.2015.11.003. PMID 26614257.
  4. ^ Samaras, N; Papadopoulou, MA; Samaras, D; Ongaro, F (2014). "Off-label use of hormones as an antiaging strategy: a review". Clinical Interventions in Aging. 9: 1175–86. doi:10.2147/CIA.S48918. PMC 4116364. PMID 25092967.
  5. ^ Shifren, JL (October 2015). "Testosterone for midlife women: the hormone of desire?". Menopause. 22 (10): 1147–9. doi:10.1097/gme.0000000000000540. PMID 26397145. S2CID 10928315.
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