Dopamine antagonist
| Dopamine receptor antagonist Dopaminergic blockers | |
|---|---|
| Drug class | |
Skeletal structural formula of Haloperidol, a typical antipsychotic | |
| Class identifiers | |
| Use | Schizophrenia, bipolar disorder, nausea and vomiting, etc. |
| ATC code | N05A |
| Biological target | Dopamine receptors |
| External links | |
| MeSH | D012559 |
| Legal status | |
| In Wikidata | |
A dopamine antagonist, also known as an anti-dopaminergic and a dopamine receptor antagonist (DRA), is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics are dopamine antagonists, and have been used in treating schizophrenia, bipolar disorder, and stimulant psychosis.[1] Several other dopamine antagonists are antiemetics used in the treatment of nausea and vomiting.
- ^ Beaulieu JM, Gainetdinov RR (March 2011). "The physiology, signaling, and pharmacology of dopamine receptors". Pharmacological Reviews. 63 (1): 182–217. doi:10.1124/pr.110.002642. PMID 21303898. S2CID 2545878.