Antimicrobial spectrum

The antimicrobial spectrum of an antibiotic means the range of microorganisms it can kill or inhibit. Antibiotics can be divided into broad-spectrum antibiotics, extended-spectrum antibiotics and narrow-spectrum antibiotics based on their spectrum of activity. Detailedly, broad-spectrum antibiotics can kill or inhibit a wide range of microorganisms; extended-spectrum antibiotic can kill or inhibit Gram positive bacteria and some Gram negative bacteria; narrow-spectrum antibiotic can only kill or inhibit limited species of bacteria.[1][2][3]

Currently no antibiotic's spectrum can completely cover all types of microorganisms.[4]

  1. ^ Michelle A. Clark; et al. (2009). Pharmacology (5th ed.). USA: Lippincott Williams & Wilkins. pp. 375–376. ISBN 978-1-4511-4320-1.
  2. ^ David Warrell; Timothy M. Cox; John Firth; Estée Török (11 October 2012). Oxford Textbook of Medicine: Infection. OUP Oxford. p. 39. ISBN 978-0-19-965213-6.
  3. ^ Melander, Roberta J.; Zurawski, Daniel V.; Melander, Christian (2018). "Narrow-Spectrum Antibacterial Agents". MedChemComm. 9 (1): 12–21. doi:10.1039/C7MD00528H. ISSN 2040-2503. PMC 5839511. PMID 29527285.
  4. ^ Erich Lück; Martin Jager (1997). Antimicrobial Food Additives: Characteristics, Uses, Effects. Springer Science & Business Media. p. 39. ISBN 978-3-540-61138-7.
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