Anxiotropic

An anxiotropic (/ˌæŋksiəˈtɹoʊpɪk/) agent is one that modifies the emotion, anxiety, which is associated with excessive worry and fear, an elevated heart rate, and feelings of irritability, restlessness, and panic. Anxiety is also a highly prevalent psychiatric condition that affects a significant portion of the population and can often have debilitating effects. Many animals also exhibit features of anxiety, specifically when presented novel or predatory stimuli. These similarities make animal models a useful tool in understanding anxiety in humans, specifically animals that are genetically similar to humans, such as rodents and zebrafish (Danio reriro).[1]

In psychopharmacology, anxiotropic agents consist of two categories of psychoactive drugs: anxiolytics that reduce anxiety and may be used therapeutically, and anxiogenic compounds that increase anxiety.

  1. ^ de Abreu, Murilo S.; Giacomini, Ana C. V. V.; Demin, Konstantin A.; Galstyan, David S.; Zabegalov, Konstantin N.; Kolesnikova, Tatyana O.; Amstislavskaya, Tamara G.; Strekalova, Tatyana; Petersen, Elena V.; Kalueff, Allan V. (2021-08-01). "Unconventional anxiety pharmacology in zebrafish: Drugs beyond traditional anxiogenic and anxiolytic spectra". Pharmacology Biochemistry and Behavior. 207: 173205. doi:10.1016/j.pbb.2021.173205. ISSN 0091-3057.