Bat SARS-like coronavirus WIV1
| Bat SARS-like coronavirus WIV1 | |
|---|---|
| Virus classification | |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Pisuviricota |
| Class: | Pisoniviricetes |
| Order: | Nidovirales |
| Family: | Coronaviridae |
| Genus: | Betacoronavirus |
| Subgenus: | Sarbecovirus |
| Species: | |
| Strain: | Bat SARS-like coronavirus WIV1
|
| Synonyms | |
| |
Bat SARS-like coronavirus WIV1 (Bat SL-CoV-WIV1), also sometimes called SARS-like coronavirus WIV1, is a strain of severe acute respiratory syndrome–related coronavirus (SARSr-CoV) isolated from Chinese rufous horseshoe bats in 2013 (Rhinolophus sinicus).[1][2] Like all coronaviruses, virions consist of single-stranded positive-sense RNA enclosed within an envelope.[3]
WIV1 was named for the Wuhan Institute of Virology, where it was discovered by a researcher on Shi Zhengli's team.[4]
In 2018, Ralph S. Baric and Vincent Munster of Rocky Mountain Laboratories infected Egyptian fruit bat (Rousettus aegyptiacus) with WIV1.[5] SARS-CoV-2 transmits efficiently in Egyptian fruit bats.[6]
- ^ Xing-Yi Ge; Jia-Lu Li; Xing-Lou Yang; et al. (2013). "Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor". Nature. 503 (7477): 535–8. Bibcode:2013Natur.503..535G. doi:10.1038/nature12711. PMC 5389864. PMID 24172901.
- ^ "Taxonomy: Bat SARS-like coronavirus WIV1". www.ncbi.nlm.nih.gov. Retrieved 2020-02-20.
- ^ Naik, Gautam (2013-10-30). "Study: Bat-to-Human Leap Likely for SARS-Like Virus - WSJ.com". Wall Street Journal. Online.wsj.com. Retrieved 2013-10-31.
- ^ Qiu, Jane. "Meet the scientist at the center of the covid lab leak controversy". MIT Technology Review. Archived from the original on 2022-02-14. Retrieved 2024-06-03.
- ^ Van Doremalen, N. (19 Dec 2018). "SARS-Like Coronavirus WIV1-CoV Does Not Replicate in Egyptian Fruit Bats (Rousettus aegyptiacus)". Viruses. 10 (12): 727. doi:10.3390/v10120727. PMC 6316779. PMID 30572566.
- ^ Schlottau, K. (September 2020). "SARS-CoV-2 in fruit bats, ferrets, pigs, and chickens: an experimental transmission study". Lancet. 1 (5): e218 – e225. doi:10.1016/S2666-5247(20)30089-6. PMC 7340389. PMID 32838346.