Benzene

Benzene
Space-filling model
Geometry
Ball and stick model
Benzene at room temperature
Names
Preferred IUPAC name
Benzene[1]
Other names
Benzol (historic/German)
Cyclohexa-1,3,5-triene; 1,3,5-Cyclohexatriene (theoretical resonance isomers)
[6]Annulene (not recommended[1])
Phene (historic)
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.000.685
EC Number
  • 200-753-7
KEGG
PubChem CID
RTECS number
  • CY1400000
UNII
InChI
  • InChI=1S/C6H6/c1-2-4-6-5-3-1/h1-6H Y
    Key: UHOVQNZJYSORNB-UHFFFAOYSA-N Y
SMILES
  • c1ccccc1
Properties
Chemical formula
C6H6
Molar mass 78.114 g·mol−1
Appearance Colorless liquid
Odor sweet aromatic
Density 0.8765(20) g/cm3[2]
Melting point 5.53 °C (41.95 °F; 278.68 K)
Boiling point 80.1 °C (176.2 °F; 353.2 K)
Solubility in water
1.53 g/L (0 °C)
1.81 g/L (9 °C)
1.79 g/L (15 °C)[3][4][5]
1.84 g/L (30 °C)
2.26 g/L (61 °C)
3.94 g/L (100 °C)
21.7 g/kg (200 °C, 6.5 MPa)
17.8 g/kg (200 °C, 40 MPa)[6]
Solubility Soluble in alcohol, CHCl3, CCl4, diethyl ether, acetone, acetic acid[6]
Solubility in ethanediol 5.83 g/100 g (20 °C)
6.61 g/100 g (40 °C)
7.61 g/100 g (60 °C)[6]
Solubility in diethylene glycol 52 g/100 g (20 °C)[6]
log P 2.13
Vapor pressure 12.7 kPa (25 °C)
24.4 kPa (40 °C)
181 kPa (100 °C)[7]
Conjugate acid Benzenium[8]
Conjugate base Benzenide[9]
UV-vis (λmax) 255 nm
Magnetic susceptibility (χ)
−54.8·10−6 cm3/mol
Refractive index (nD)
1.5011 (20 °C)
1.4948 (30 °C)[6]
Viscosity 0.7528 cP (10 °C)
0.6076 cP (25 °C)
0.4965 cP (40 °C)
0.3075 cP (80 °C)
Structure
Molecular shape
Trigonal planar
Dipole moment
0 D
Thermochemistry
Heat capacity (C)
134.8 J/mol·K
Std molar
entropy (S298)
173.26 J/mol·K[7]
Std enthalpy of
formation fH298)
48.7 kJ/mol
Std enthalpy of
combustion cH298)
−3267.6 kJ/mol[7]
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
potential occupational carcinogen, flammable
GHS labelling:
Pictograms
[10]
Signal word
Danger
Hazard statements
H225, H302, H304, H305, H315, H319, H340, H350, H372, H410[10]
Precautionary statements
P201, P210, P301+P310, P305+P351+P338, P308+P313, P331[10]
NFPA 704 (fire diamond)
2
3
0
Flash point −11.63 °C (11.07 °F; 261.52 K)
Autoignition
temperature
497.78 °C (928.00 °F; 770.93 K)
Explosive limits 1.2–7.8%
Lethal dose or concentration (LD, LC):
930 mg/kg (rat, oral)[12]
44,000 ppm (rabbit, 30 min)
44,923 ppm (dog)
52,308 ppm (cat)
20,000 ppm (human, 5 min)[13]
NIOSH (US health exposure limits):
PEL (Permissible)
TWA 1 ppm, ST 5 ppm[11]
REL (Recommended)
Ca TWA 0.1 ppm ST 1 ppm[11]
IDLH (Immediate danger)
500 ppm[11]
Safety data sheet (SDS) HMDB
Related compounds
Related compounds
Toluene
Borazine
Supplementary data page
Benzene (data page)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references

Benzene is an organic chemical compound with the molecular formula C6H6. The benzene molecule is composed of six carbon atoms joined in a planar hexagonal ring with one hydrogen atom attached to each. Because it contains only carbon and hydrogen atoms, benzene is classed as a hydrocarbon.

Benzene is a natural constituent of petroleum and is one of the elementary petrochemicals. Due to the cyclic continuous pi bonds between the carbon atoms and satisfying Hückel's rule, benzene is classed as an aromatic hydrocarbon. Benzene is a colorless and highly flammable liquid with a sweet smell, and is partially responsible for the aroma of gasoline. It is used primarily as a precursor to the manufacture of chemicals with more complex structures, such as ethylbenzene and cumene, of which billions of kilograms are produced annually. Although benzene is a major industrial chemical, it finds limited use in consumer items because of its toxicity. Benzene is a volatile organic compound.[14]

Benzene is classified as a carcinogen. Its particular effects on human health, such as the long-term results of accidental exposure, have been reported on by news organizations such as The New York Times. For instance, a 2022 article stated that benzene contamination in the Boston metropolitan area caused hazardous conditions in multiple places, with the publication noting that the compound may eventually cause leukemia in some individuals.[15]

  1. ^ a b Favre, Henri A.; Powell, Warren H. (2014). Nomenclature of Organic Chemistry: IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. pp. 10, 22, 204, 494, 577. doi:10.1039/9781849733069. ISBN 978-0-85404-182-4.
  2. ^ Lide, D. R., ed. (2005). CRC Handbook of Chemistry and Physics (86th ed.). Boca Raton, Florida: CRC Press. ISBN 0-8493-0486-5.
  3. ^ Arnold, D.; Plank, C.; Erickson, E.; Pike, F. (1958). "Solubility of Benzene in Water". Industrial & Engineering Chemistry Chemical & Engineering Data Series. 3 (2): 253–256. doi:10.1021/i460004a016.
  4. ^ Breslow, R.; Guo, T. (1990). "Surface tension measurements show that chaotropic salting-in denaturants are not just water-structure breakers". Proceedings of the National Academy of Sciences of the United States of America. 87 (1): 167–9. Bibcode:1990PNAS...87..167B. doi:10.1073/pnas.87.1.167. PMC 53221. PMID 2153285.
  5. ^ Coker, A. Kayode; Ludwig, Ernest E. (2007). Ludwig's Applied Process Design for Chemical And Petrochemical Plants. Vol. 1. Elsevier. p. 114. ISBN 978-0-7506-7766-0. Archived from the original on 2016-03-12. Retrieved 2012-05-31.
  6. ^ a b c d e "Benzol". Archived from the original on 2014-05-29. Retrieved 2014-05-29.
  7. ^ a b c Benzene in Linstrom, Peter J.; Mallard, William G. (eds.); NIST Chemistry WebBook, NIST Standard Reference Database Number 69, National Institute of Standards and Technology, Gaithersburg (MD) (retrieved 2014-05-29)
  8. ^ "Benzenium (CID 12533897". PubChem. February 8, 2007. Retrieved September 18, 2022.
  9. ^ "Benzenide (CID 5150480)". PubChem. June 24, 2005. Retrieved September 18, 2022.
  10. ^ a b c Sigma-Aldrich Co., Benzene Archived 2016-12-01 at the Wayback Machine. Retrieved on 2014-05-29.
  11. ^ a b c NIOSH Pocket Guide to Chemical Hazards. "#0049". National Institute for Occupational Safety and Health (NIOSH).
  12. ^ MSDS
  13. ^ "Benzene". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
  14. ^ "Benzene fact sheet". CDC. 2 September 2021. Retrieved 16 Aug 2023.
  15. ^ Shao, Elena (28 June 2022). "Gas Piped into Homes Contains Benzene and Other Risky Chemicals, Study Finds". The New York Times.