Benzestrol

Benzestrol
Clinical data
Trade names	Chemestrogen, Ocestrol, Octestrol, Octoestrol, Octofollin
Drug class	Nonsteroidal estrogen
Identifiers
	IUPAC name 4,4'-(3-ethylhexane-2,4-diyl)diphenol;
CAS Number	85-95-0;
PubChem CID	6827;
ChemSpider	6566;
UNII	A27512LR47;
ChEBI	CHEBI:135264;
ChEMBL	ChEMBL2104644;
CompTox Dashboard (EPA)	DTXSID50861663 ;
Chemical and physical data
Formula	C20H26O2
Molar mass	298.426 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC(C1=CC=C(C=C1)O)C(CC)C(C)C2=CC=C(C=C2)O;
	InChI InChI=InChI=1S/C20H26O2/c1-4-19(14(3)15-6-10-17(21)11-7-15)20(5-2)16-8-12-18(22)13-9-16/h6-14,19-22H,4-5H2,1-3H3; Key:DUTFBSAKKUNBAL-UHFFFAOYSA-N;

Benzestrol (INNTooltip International Nonproprietary Name, BANTooltip British Approved Name) (brand names Chemestrogen, Ocestrol, Octestrol, Octoestrol, Octofollin) is a synthetic nonsteroidal estrogen of the stilbestrol group which was formerly used medically but has since been discontinued.^[1]^[2]^[3] The stilbestrol estrogens, the best-known of which is diethylstilbestrol (DES) were used extensively in the mid-1900s and were finally banned by the FDA due to them causing tumors in the children of women who used them.^[4]

^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 133–. ISBN 978-1-4757-2085-3.
^ Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 47–. ISBN 978-94-011-4439-1.
^ "Benzestrol". Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 106–. ISBN 978-3-88763-075-1.
^ "DES History". U.S. Centers for Disease Control and Prevention. Archived from the original on 15 June 2019. Retrieved 17 December 2012.

[Elks2014-1] Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 133–. ISBN 978-1-4757-2085-3.

[MortonHall2012-2] Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 47–. ISBN 978-94-011-4439-1.

[3] "Benzestrol". Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 106–. ISBN 978-3-88763-075-1.

[cdc-4] "DES History". U.S. Centers for Disease Control and Prevention. Archived from the original on 15 June 2019. Retrieved 17 December 2012.

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