Bezlotoxumab

Bezlotoxumab
Monoclonal antibody
TypeWhole antibody
SourceHuman
TargetClostridioides difficile toxin B
Clinical data
Trade namesZinplava
AHFS/Drugs.comMonograph
MedlinePlusa617003
License data
Pregnancy
category
  • AU: B2
Routes of
administration
Intravenous
ATC code
Legal status
Legal status
Identifiers
CAS Number
DrugBank
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
FormulaC6464H9974N1726O2014S46
Molar mass145565.72 g·mol−1

Bezlotoxumab, sold under the brand name Zinplava, is a human monoclonal antibody designed for the prevention of recurrence of Clostridioides difficile infections.[3][4] Bezlotoxumab binds to Clostridioides difficile toxin B.[3]

  1. ^ "Prescription medicines: registration of new chemical entities in Australia, 2017". Therapeutic Goods Administration (TGA). 21 June 2022. Retrieved 9 April 2023.
  2. ^ "Prescription medicines and biologicals: TGA annual summary 2017". Therapeutic Goods Administration (TGA). 21 June 2022. Retrieved 31 March 2024.
  3. ^ a b c "Zinplava- bezlotoxumab injection, solution". DailyMed. 26 May 2023. Retrieved 20 October 2024.
  4. ^ "Statement On A Nonproprietary Name Adopted By The USAN Council - Bezlotoxumab" (PDF). American Medical Association. Archived from the original on 16 September 2012. Retrieved 25 October 2012.