Binswanger's disease
| Binswanger's disease | |
|---|---|
| Other names | Subcortical arteriosclerotic encephalopathy |
| Specialty | Neurology |
| Symptoms | Cognitive impairment, ataxia, slowness of movement, problems with language, bradyphrenia |
Binswanger's disease, also known as subcortical leukoencephalopathy and subcortical arteriosclerotic encephalopathy,[1] is a form of small-vessel vascular dementia caused by damage to the white brain matter.[2] White matter atrophy can be caused by many circumstances including chronic hypertension as well as old age.[3] This disease is characterized by loss of memory and intellectual function and by changes in mood. These changes encompass what are known as executive functions of the brain.[4] It usually presents between 54 and 66 years of age, and the first symptoms are usually mental deterioration or stroke.[5]
It was described by Otto Binswanger in 1894, and[6] Alois Alzheimer first used the phrase "Binswanger's disease" in 1902.[7] However, Jerzy Olszewski is credited with much of the modern-day investigation of this disease which began in 1962.[5][8]
- ^ van der Knaap, MS; Valk, J (1995). "Subcortical Arteriosclerotic Encephalopathy". Magnetic resonance of myelin, myelination, and myelin disorders (2nd ed.). Berlin, Heidelberg: Springer. doi:10.1007/978-3-662-03078-3_65. ISBN 978-3-662-03078-3.
- ^ Akiguchi I, Tomimoto H, Suenaga T, Wakita H, Budka H (July 1997). "Alterations in glia and axons in the brains of Binswanger's disease patients". Stroke. 28 (7): 1423–9. doi:10.1161/01.str.28.7.1423. PMID 9227695.
- ^ Giovannetti, T. Personal Interview. 16 October 2009
- ^ Shapiro DE, Boggs SR, Melamed BG, Graham-Pole J (1992). "The effect of varied physician affect on recall, anxiety, and perceptions in women at risk for breast cancer: an analogue study". Health Psychol. 11 (1): 61–6. doi:10.1037/0278-6133.11.1.61. PMID 1559536. S2CID 207733.
- ^ a b Loeb C (2000). "Binswanger's disease is not a single entity". Neurol. Sci. 21 (6): 343–8. doi:10.1007/s100720070048. PMID 11441570. S2CID 8914783. Archived from the original on 2013-01-04.
- ^ Pantoni L, Moretti M, Inzitari D (1996). "The first Italian report on "Binswanger's disease"". Ital J Neurol Sci. 17 (5): 367–70. doi:10.1007/BF01999900. PMID 8933231. S2CID 22502909.
- ^ "Review: Binswanger's disease, leuokoaraiosis and dementia". Age and Ageing. 1994. Retrieved 2008-01-30.
- ^ Olszewski J (1962). "Subcortical arteriosclerotic encephalopathy. Review of the literature on the so-called Binswanger's disease and presentation of two cases". World Neurol. 3: 359–75. PMID 14481961.