Biotin

Biotin
Names
	Preferred IUPAC name 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid
	Other names Vitamin B7
Identifiers
CAS Number	58-85-5 ;
3D model (JSmol)	Interactive image; Interactive image;
ChEBI	CHEBI:15956 ;
ChEMBL	ChEMBL857 ;
ChemSpider	149962 ;
DrugBank	DB00121 ;
ECHA InfoCard	100.000.363
IUPHAR/BPS	4787;
KEGG	D00029 ;
PubChem CID	171548;
UNII	6SO6U10H04 ;
CompTox Dashboard (EPA)	DTXSID7022679 ;
	InChI InChI=1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1 Key: YBJHBAHKTGYVGT-ZKWXMUAHSA-N ; InChI=1/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1 Key: YBJHBAHKTGYVGT-ZKWXMUAHBB;
	SMILES O=C1N[C@@H]2[C@@H](SC[C@@H]2N1)CCCCC(=O)O; C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)O)NC(=O)N2;
Properties
Chemical formula	C10H16N2O3S
Molar mass	244.31 g·mol−1
Appearance	White crystalline needles
Melting point	232 to 233 °C (450 to 451 °F; 505 to 506 K)
Solubility in water	22 mg/100 mL
Pharmacology
ATC code	A11HA05 (WHO)
Hazards
NFPA 704 (fire diamond)	1 1 0
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Biotin (also known as vitamin B₇) is one of the B vitamins – a group of essential dietary micronutrients.^[1]^[2] Present in every living cell, it is involved as a cofactor for enzymes in numerous metabolic processes, both in humans and in other organisms, primarily related to the biochemistry of fats, carbohydrates, and amino acids.^[1]^[2]^[3]

When isolated, biotin is a white, needle-like crystalline solid.^[4] Biotin is obtained from foods, particularly meats and liver, and is sold as a dietary supplement.^[1]

The name biotin, borrowed from the German biotin, derives from the Ancient Greek word βίοτος (bíotos; 'life') and the suffix "-in" (a suffix used in chemistry usually to indicate 'forming').^[5]

^ ^a ^b ^c "Biotin – Fact Sheet for Health Professionals". Office of Dietary Supplements, US National Institutes of Health. January 10, 2022. Retrieved August 3, 2025.
^ ^a ^b "Biotin". Micronutrient Information Center, Linus Pauling Institute, Oregon State University, Corvallis, OR. 2025. Retrieved August 3, 2025.
^ Penberthy WT, Sadri M, Zempleni J (2020). "Biotin". In BP Marriott, DF Birt, VA Stallings, AA Yates (eds.). Present Knowledge in Nutrition, Eleventh Edition. London, United Kingdom: Academic Press (Elsevier). pp. 289–304. ISBN 978-0-323-66162-1.
^ "Biotin". US National Library of Medicine. August 2, 2025. Retrieved August 3, 2025.
^ "Biotin". Online Etymology Dictionary. 2025. Retrieved August 3, 2025.

[ods-1] "Biotin – Fact Sheet for Health Professionals". Office of Dietary Supplements, US National Institutes of Health. January 10, 2022. Retrieved August 3, 2025.

[lpi-2] "Biotin". Micronutrient Information Center, Linus Pauling Institute, Oregon State University, Corvallis, OR. 2025. Retrieved August 3, 2025.

[PKIN2020Biotin-3] Penberthy WT, Sadri M, Zempleni J (2020). "Biotin". In BP Marriott, DF Birt, VA Stallings, AA Yates (eds.). Present Knowledge in Nutrition, Eleventh Edition. London, United Kingdom: Academic Press (Elsevier). pp. 289–304. ISBN 978-0-323-66162-1.

[pubchem-4] "Biotin". US National Library of Medicine. August 2, 2025. Retrieved August 3, 2025.

[Etymology-5] "Biotin". Online Etymology Dictionary. 2025. Retrieved August 3, 2025.

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