Bithionol

Bithionol
Clinical data
Other names	2,4-dichloro- 6-(3,5-dichloro- 2-hydroxyphenyl)sulfanylphenol
ATC code	D10AB01 (WHO) P02BX01 (WHO) QP52AG07 (WHO);
Identifiers
	IUPAC name 2,2'-sulfanediylbis(4,6-dichlorophenol);
CAS Number	97-18-7 ;
PubChem CID	2406;
IUPHAR/BPS	2338;
DrugBank	DB04813 ;
ChemSpider	2313 ;
UNII	AMT77LS62O;
KEGG	C07967;
ChEBI	CHEBI:3131 ;
ChEMBL	ChEMBL290106 ;
CompTox Dashboard (EPA)	DTXSID9021342 ;
ECHA InfoCard	100.002.333
Chemical and physical data
Formula	C12H6Cl4O2S
Molar mass	356.04 g·mol−1
3D model (JSmol)	Interactive image;
Melting point	188 °C (370 °F)
	SMILES Clc2cc(Cl)cc(Sc1cc(Cl)cc(Cl)c1O)c2O;
	InChI InChI=1S/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H ; Key:JFIOVJDNOJYLKP-UHFFFAOYSA-N ;
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Bithionol is an antibacterial, anthelmintic, and algaecide. It is used to treat Anoplocephala perfoliata (tapeworms) in horses^[1] and Fasciola hepatica (liver flukes).

^ Sanada Y, Senba H, Mochizuki R, Arakaki H, Gotoh T, Fukumoto S, Nagahata H (May 2009). "Evaluation of marked rise in fecal egg output after bithionol administration to horse and its application as a diagnostic marker for equine Anoplocephala perfoliata infection". The Journal of Veterinary Medical Science. 71 (5): 617–620. doi:10.1292/jvms.71.617. PMID 19498288.

[1] Sanada Y, Senba H, Mochizuki R, Arakaki H, Gotoh T, Fukumoto S, Nagahata H (May 2009). "Evaluation of marked rise in fecal egg output after bithionol administration to horse and its application as a diagnostic marker for equine Anoplocephala perfoliata infection". The Journal of Veterinary Medical Science. 71 (5): 617–620. doi:10.1292/jvms.71.617. PMID 19498288.

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