Bitot's spots

Bitot's spots
Other namesICD10 = E50.1
Bitot's spot
Typical location of Bitot's spots
SpecialtyOphthalmology 

Bitot's spots are the buildup of keratin located superficially in the conjunctiva of human's eyes. They can be oval, triangular or irregular in shape. The spots are a sign of vitamin A deficiency and associated with drying of the cornea. In 1863, the French physician Pierre Bitot (1822–1888) first described these spots.[1] The spots may abate under replacement therapy.[2] In ancient Egypt, this was treated with animal liver, which is where vitamin A is stored.[3]

  1. ^ Shukla, M; Behari, K (Jul 1979). "Congenital Bitot spots". Indian Journal of Ophthalmology. 27 (2): 63–4. PMID 541036.
  2. ^ Ram, Jagat; Jinagal, Jitender (2018). "Bitot's Spots". New England Journal of Medicine. 379 (9): 869. doi:10.1056/NEJMicm1715354. PMID 30157394. S2CID 52126826.
  3. ^ Numitor, Gerd (February 2012). Bitot's Spots. Flu Press. ISBN 978-620-0-57824-2.