Body fluid

Body fluids, bodily fluids, or biofluids, sometimes body liquids, are liquids within the body of an organism.[1] In lean healthy adult men, the total body water is about 60% (60–67%) of the total body weight; it is usually slightly lower in women (52–55%).[2][3] The exact percentage of fluid relative to body weight is inversely proportional to the percentage of body fat. A lean 70 kg (150 lb) man, for example, has about 42 (42–47) liters of water in his body.

The total body of water is divided into fluid compartments,[1] between the intracellular fluid compartment (also called space, or volume) and the extracellular fluid (ECF) compartment (space, volume) in a two-to-one ratio: 28 (28–32) liters are inside cells and 14 (14–15) liters are outside cells.

The ECF compartment is divided into the interstitial fluid volume – the fluid outside both the cells and the blood vessels – and the intravascular volume (also called the vascular volume and blood plasma volume) – the fluid inside the blood vessels – in a three-to-one ratio: the interstitial fluid volume is about 12 liters; the vascular volume is about 4 liters.

The interstitial fluid compartment is divided into the lymphatic fluid compartment – about 2/3, or 8 (6–10) liters, and the transcellular fluid compartment (the remaining 1/3, or about 4 liters).[4]

The vascular volume is divided into the venous volume and the arterial volume; and the arterial volume has a conceptually useful but unmeasurable subcompartment called the effective arterial blood volume.[5]

  1. ^ a b "body fluid". Taber's online – Taber's medical dictionary. Archived from the original on 2021-06-21. Retrieved 2021-06-22.
  2. ^ "The water in you". Howard Perlman. December 2016.
  3. ^ Lote, Christopher J. Principles of Renal Physiology, 5th edition. Springer. p. 2.
  4. ^ Santambrogio, Laura (2018). "The Lymphatic Fluid". International Review of Cell and Molecular Biology. 337: 111–133. doi:10.1016/bs.ircmb.2017.12.002. ISBN 9780128151952. PMID 29551158.
  5. ^ Vesely, David L (2013). "Natriuretic Hormones". Seldin and Giebisch's the Kidney: 1241–1281. doi:10.1016/B978-0-12-381462-3.00037-9. ISBN 9780123814623.
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