Brachyspira
| Brachyspira | |
|---|---|
| Scientific classification | |
| Domain: | Bacteria |
| Kingdom: | Pseudomonadati |
| Phylum: | Spirochaetota |
| Class: | Spirochaetia |
| Order: | Brachyspirales |
| Family: | Brachyspiraceae |
| Genus: | Hovind-Hougen et al. 1983 non Foliella non Pfeiffer 1855 |
| Type species | |
| Brachyspira aalborgi Hovind-Hougen et al. 1983
| |
| Species | |
|
See text. | |
| Synonyms | |
| |
Brachyspira is a genus of bacteria classified within the phylum Spirochaetota.[1][2] [3]
Brachyspira species include pathogens in pigs, birds, dogs, and humans.
B. pilosicoli colonizes millions of humans worldwide, leading to human intestinal spirochaetosis, a chronic, intermittent watery diarrhea vastly underdiagnosed [4] because of the lack of a simple diagnostic tool for clinicians. Multiplex qPCRs are promising diagnostic tools, as Brachyspira do not grow on conventional media.[5]
B. pilosicoli also cause avian spirochetosis:[1] birds might be considered as the natural reservoir.
B. hyodysenteriae leads to diarrheal disease in growing pigs worldwide, causing the so-called swine dysentery, typhlocolitis or porcine intestinal spirochaetosis, which contributes to major "production losses" in agrobusiness.
Some species like B. innocens or B. intermedia seem to be less virulent.
- ^ a b Le Roy, Caroline I.; Mappley, Luke J.; La Ragione, Roberto M.; Woodward, Martin J.; Claus, Sandrine P. (5 March 2019). "Brachyspira pilosicoli-induced avian intestinal spirochaetosis". Microbial Ecology in Health and Disease. 26: 28853. doi:10.3402/mehd.v26.28853. PMC 4683989. PMID 26679774.
- ^ See the List of Prokaryotic names with Standing in Nomenclature. Data extracted from J.P. Euzéby. "Spirochaetes". Archived from the original on 2011-06-13. Retrieved 2011-11-17.
- ^ See the NCBI webpage on Spirochaetes Data extracted from Sayers; et al. "NCBI Taxonomy Browser". National Center for Biotechnology Information. Retrieved 2011-06-05.
- ^ Hampson, David J. (2017). "The Spirochete Brachyspira pilosicoli, Enteric Pathogen of Animals and Humans". Clinical Microbiology Reviews. 31 (1). doi:10.1128/CMR.00087-17. PMC 5740978. PMID 29187397.
- ^ Borgström, Anna; Scherrer, Simone; Kirchgässner, Constanze; Schmitt, Sarah; Frei, Daniel; Wittenbrink, Max M. (7 February 2017). "A novel multiplex qPCR targeting 23S rDNA for diagnosis of swine dysentery and porcine intestinal spirochaetosis". BMC Veterinary Research. 13 (1): 42. doi:10.1186/s12917-016-0939-6. PMC 5297149. PMID 28173799.