Brain ischemia

Brain ischemia
Other namesCerebral ischemia, cerebrovascular ischemia
SpecialtyNeurology, cardiology 

Brain ischemia is a condition in which there is insufficient bloodflow to the brain to meet metabolic demand.[1] This leads to poor oxygen supply in the brain and may be temporary such as in transient ischemic attack or permanent in which there is death of brain tissue such as in cerebral infarction (ischemic stroke).[2]

The symptoms of brain ischemia reflect the anatomical region undergoing blood and oxygen deprivation, and may involve impairments in vision, body movement, and speaking.

An interruption of blood flow to the brain for more than 10 seconds causes unconsciousness, and an interruption in flow for more than a few minutes generally results in irreversible brain damage.[3] In 1974, Hossmann and Zimmermann demonstrated that ischemia induced in mammalian brains for up to an hour can be at least partially recovered.[4] Accordingly, this discovery raised the possibility of intervening after brain ischemia before the damage becomes irreversible.[5]

  1. ^ Sullivan, Jonathon. "What is Brain Ischemia?". WSU Emergency Medicine Cerebral Resuscitation Laboratory. Archived from the original on 2009-01-06. Retrieved 2008-11-11.
  2. ^ "Brain Ischemia (Cerebral Ischemia)". Cure Hunter Incorporated. 2003. pp. Relationship Network. Archived from the original on 2009-02-14. Retrieved 2008-11-11.
  3. ^ Raichle, Marcus (1983). "The Pathophysiology of Brain Ischemia" (PDF). Neurological Progress. Archived from the original (PDF) on 2009-02-19. Retrieved 2008-11-11.
  4. ^ Hossmann, Konstantin-Alexander; Zimmermann, Volker (1974). "Resuscitation of the monkey brain after 1 H complete ischemia. I. Physiological and morphological observations". Brain Research. 81 (1): 59–74. doi:10.1016/0006-8993(74)90478-8. PMID 4434196.
  5. ^ Raichle, Marcus; Ann Neurol (1983). "The pathophysiology of brain ischemia" (PDF). Neurological Process. Archived from the original (PDF) on 2009-02-19. Retrieved 2009-04-22.
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