Briakinumab
| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Human |
| Target | IL-12 and IL-23 |
| Clinical data | |
| ATC code | |
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| Pharmacokinetic data | |
| Bioavailability | N/A |
| Identifiers | |
| CAS Number | |
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| Chemical and physical data | |
| Formula | C6376H9874N1722O1992S44 |
| Molar mass | 143935.83 g·mol−1 |
| (what is this?) (verify) | |
Briakinumab (ABT-874) is a human monoclonal antibody being developed by Abbott Laboratories for the treatment of rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis. As of 2011 drug development for psoriasis has been discontinued in the U.S. and Europe.[1]
Like ustekinumab, the antibody targets the interleukins 12 and 23.[2]
- ^ "Abbott withdraws briakinumab applications in USA, Europe". PharmaTimes. 17 January 2011. Archived from the original on 17 April 2011.
- ^ Lima XT, Abuabara K, Kimball AB, Lima HC (August 2009). "Briakinumab". Expert Opinion on Biological Therapy. 9 (8): 1107–13. doi:10.1517/14712590903092188. PMID 19569977. S2CID 219184448.