CYP17A1 inhibitor
| CYP17A1 inhibitor | |
|---|---|
| Drug class | |
Abiraterone acetate, a steroidal CYP17A1 inhibitor that is used in the treatment of prostate cancer. | |
| Class identifiers | |
| Synonyms | Androgen synthesis inhibitors |
| Use | Prostate cancer, precocious puberty, breast cancer, others |
| ATC code | L02BX |
| Biological target | CYP17A1 |
| Chemical class | Steroidal; Nonsteroidal |
| Legal status | |
| In Wikidata | |
A CYP17A1 inhibitor is a type of drug that inhibits the enzyme CYP17A1.[1] CYP17A1 inhibitors work by blocking specific enzyme functions, impacting androgen biosynthesis.
- ^ Malikova J, Brixius-Anderko S, Udhane SS, Parween S, Dick B, Bernhardt R, et al. (November 2017). "CYP17A1 inhibitor abiraterone, an anti-prostate cancer drug, also inhibits the 21-hydroxylase activity of CYP21A2". The Journal of Steroid Biochemistry and Molecular Biology. 174: 192–200. doi:10.1016/j.jsbmb.2017.09.007. PMID 28893623. S2CID 6270824.