Calcium pyrophosphate dihydrate crystal deposition disease

Calcium pyrophosphate dihydrate disease
Other namesPseudogout
Polarized light microscopy of CPPD, showing rhombus-shaped calcium pyrophosphate crystals with positive birefringence.

Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease, also known as pseudogout and pyrophosphate arthropathy, is a rheumatologic disease which is thought to be secondary to abnormal accumulation of calcium pyrophosphate dihydrate crystals within joint soft tissues.[1] The knee joint is most commonly affected.[2] The disease is metabolic in origin and its treatment remains symptomatic.[3]

  1. ^ Cite error: The named reference Wright1997 was invoked but never defined (see the help page).
  2. ^ Cite error: The named reference emedicine1 was invoked but never defined (see the help page).
  3. ^ Abhishek A, Doherty M (2016). "Update on calcium pyrophosphate deposition". Clinical and Experimental Rheumatology. 34 (4 Suppl 98): 32–38. PMID 27586801.
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