Camidanlumab tesirine
Chemical structure of tesirine (black) linked to a cysteine of camidanlumab (blue) | |
| Monoclonal antibody | |
|---|---|
| Type | ? |
| Source | Human |
| Target | CD25 |
| Clinical data | |
| Other names | ADCT-301 |
| ATC code |
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| Identifiers | |
| CAS Number | |
| ChemSpider |
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| UNII | |
| KEGG | |
| Chemical and physical data | |
| Formula | C6548H10150N1732O2038S42 |
| Molar mass | 147091.83 g·mol−1 |
Camidanlumab tesirine (Cami-T or ADCT-301) is an antibody-drug conjugate (ADC) composed of a human antibody that binds to the protein CD25, conjugated to a pyrrolobenzodiazepine dimer toxin. The experimental drug, developed by ADC Therapeutics is being tested in clinical trials for the treatment of B-cell Hodgkin's lymphoma (HL) and non-Hodgkin lymphoma (NHL), and for the treatment of B-cell acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML).