Cantú syndrome

Cantú syndrome
Other namesHypertrychotic osteochondrodysplasia[1]
This photo shows a person with Cantú syndrome, who has coarse facial features that are characteristic of this syndrome.
SymptomsCardiomegaly[2]
CausesMutation in ABCC9 gene[3]
Diagnostic methodEchocardiogram, X-ray[4]
TreatmentScoliosis is managed via bracing[5]

Cantú syndrome is a rare condition characterized by hypertrichosis, osteochondrodysplasia, and cardiomegaly.[6][5] Fewer than 50 cases have been described in the literature; they are associated with a mutation in the ABCC9-gene that codes for the ABCC9-protein.[5]

  1. ^ "OMIM Entry - # 239850 - CANTU SYNDROME". omim.org. Archived from the original on 2019-03-30. Retrieved 2017-04-01.
  2. ^ Cite error: The named reference gar was invoked but never defined (see the help page).
  3. ^ Cite error: The named reference genh was invoked but never defined (see the help page).
  4. ^ Cite error: The named reference kir was invoked but never defined (see the help page).
  5. ^ a b c Grange, Dorothy K.; Nichols, Colin G.; Singh, Gautam K. (1993-01-01). "Cantú Syndrome and Related Disorders". In Pagon, Roberta A.; Adam, Margaret P.; Ardinger, Holly H.; Wallace, Stephanie E.; Amemiya, Anne; Bean, Lora J.H.; Bird, Thomas D.; Ledbetter, Nikki; Mefford, Heather C. (eds.). GeneReviews. Seattle (WA): University of Washington, Seattle. PMID 25275207. Archived from the original on 2020-08-13. Retrieved 2017-08-30.Initial posting 2014
  6. ^ Engels H, Bosse K, Ehrbrecht A, et al. (August 2002). "Further case of Cantú syndrome: exclusion of cryptic subtelomeric chromosome aberrations". Am. J. Med. Genet. 111 (2): 205–9. doi:10.1002/ajmg.10560. PMID 12210352.