Catumaxomab

Catumaxomab
Monoclonal antibody
TypeTrifunctional antibody
SourceRat/mouse hybrid
TargetEpCAM, CD3
Clinical data
Trade namesRemovab, others
AHFS/Drugs.comInternational Drug Names
Routes of
administration
intraperitoneal infusion
ATC code
Legal status
Legal status
  • EU: Rx-only[1][2]
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
DrugBank
ChemSpider
  • none
UNII
 NY (what is this?)  (verify)

Catumaxomab, sold under the brand name Removab among others, is a rat-mouse hybrid monoclonal antibody which is used to treat malignant ascites, a condition occurring in people with metastasizing cancer. It binds to antigens CD3 and EpCAM. It was developed by Fresenius Biotech and Trion Pharma (Germany).[3]

  1. ^ Cite error: The named reference Korjuny EPAR was invoked but never defined (see the help page).
  2. ^ Cite error: The named reference Korjuny PI was invoked but never defined (see the help page).
  3. ^ Linke R, Klein A, Seimetz D (2010). "Catumaxomab: clinical development and future directions". mAbs. 2 (2): 129–36. doi:10.4161/mabs.2.2.11221. PMC 2840231. PMID 20190561.