Cefadroxil

Cefadroxil
Clinical data
Trade names	Duricef
AHFS/Drugs.com	Monograph
MedlinePlus	a682730
Routes of; administration	Oral
ATC code	J01DB05 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Pharmacokinetic data
Protein binding	plasma protein
Metabolism	unknown
Elimination half-life	1.5 hours
Identifiers
	IUPAC name (6R,7R)-7-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;
CAS Number	66592-87-8 ;
PubChem CID	47964;
DrugBank	DB01140 ;
ChemSpider	43629 ;
UNII	280111G160;
KEGG	D02353 ;
ChEBI	CHEBI:53667 ;
ChEMBL	ChEMBL1644 ;
CompTox Dashboard (EPA)	DTXSID8022749 ;
ECHA InfoCard	100.051.397
Chemical and physical data
Formula	C16H17N3O5S
Molar mass	363.39 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccc(O)cc3)N)C)C(=O)O.O;
	InChI InChI=1S/C16H17N3O5S.H2O/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8;/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24);1H2/t10-,11-,15-;/m1./s1 ; Key:NBFNMSULHIODTC-CYJZLJNKSA-N ;
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Cefadroxil (formerly trademarked as Duricef) is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections. It is a bactericidal antibiotic.

It was patented in 1967 and approved for medical use in 1978.^[1]

^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 493. ISBN 9783527607495.