Charcot–Bouchard aneurysm
| Charcot–Bouchard aneurysm | |
|---|---|
| Other names | Miliary aneurysms, Microaneurysms |
| Specialty | Cardiology |
| Diagnostic method | CT or MRI brain scan |
Charcot–Bouchard aneurysms are aneurysms of the brain vasculature which occur in small blood vessels (less than 300 micrometre diameter). Charcot–Bouchard aneurysms are most often located in the lenticulostriate vessels of the basal ganglia and are associated with chronic hypertension.[1] Charcot–Bouchard aneurysms are a common cause of cerebral hemorrhage. Charcot–Bouchard aneurysm rupture might be linked to senile plaque formation in the Alzheimer's disease.[2]
Retinal microaneurysms are seen in conditions like diabetic retinopathy,[3]: 498 HIV related retinal microangiopathy,[3]: 467 sickle cell retinopathy,[3]: 533 idiopathic macular telangiectasia[3]: 601 etc. In diabetic retinopathy, due to breakdown in blood–retinal barrier, microaneurysms may leak plasma constituents into the retina, or it may thrombose.[3]: 498
- ^ Fausto, [ed. by] Vinay Kumar; Abul K. Abbas; Nelson (2005). Robbins and Cotran Pathologic Basis of Disease (7th ed.). Philadelphia: Elsevier/Saunders. ISBN 978-0-7216-0187-8.
{{cite book}}: CS1 maint: multiple names: authors list (link) - ^ Fu, Hualin; Li, Jilong; Du, Peng; Jin, Weilin; Gao, Guo; Cui, Daxiang (April 2023). "Senile plaques in Alzheimer's disease arise from Aβ- and Cathepsin D-enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture". FEBS Letters. 597 (7): 1007–1040. doi:10.1002/1873-3468.14549. ISSN 0014-5793. PMID 36448495. S2CID 254095098.
- ^ a b c d e Salmon, John F. (2020). Kanski's clinical ophthalmology: a systematic approach (9th ed.). [Edinburgh]. ISBN 978-0-7020-7713-5. OCLC 1131846767.
{{cite book}}: CS1 maint: location missing publisher (link)