Chloroprocaine

Chloroprocaine
Clinical data
Trade names	Nesacaine, others
AHFS/Drugs.com	Hcl: Monograph; Ophthalmic: Multum Consumer Information;
License data	US DailyMed: Chloroprocaine;
Routes of; administration	Intrathecal, eye drop
Drug class	Local anesthetic
ATC code	N01BA04 (WHO) S01HA08 (WHO);
Legal status
Legal status	CA: ℞-only; US: ℞-only; Rx-only;
Identifiers
	IUPAC name 2-diethylaminoethyl-4-amino-2-chloro-benzoate;
CAS Number	133-16-4 ; 3858-89-7;
PubChem CID	8612; 441348;
IUPHAR/BPS	7145;
DrugBank	DB01161 ; DBSALT000823;
ChemSpider	8293 ;
UNII	5YVB0POT2H; LT7Z1YW11H;
KEGG	D07678 ; D00732;
ChEBI	CHEBI:3636 ; CHEBI:3637;
ChEMBL	ChEMBL1179047 ; ChEMBL944;
CompTox Dashboard (EPA)	DTXSID8022799 ;
Chemical and physical data
Formula	C13H19ClN2O2
Molar mass	270.76 g·mol−1
3D model (JSmol)	Interactive image; Interactive image;
	SMILES CCN(CC)CCOC(=O)C1=C(Cl)C=C(N)C=C1; ; Cl.CCN(CC)CCOC(=O)C1=C(Cl)C=C(N)C=C1;
	InChI InChI=1S/C13H19ClN2O2/c1-3-16(4-2)7-8-18-13(17)11-6-5-10(15)9-12(11)14/h5-6,9H,3-4,7-8,15H2,1-2H3 ; Key:VDANGULDQQJODZ-UHFFFAOYSA-N ; ; InChI=1S/C13H19ClN2O2.ClH/c1-3-16(4-2)7-8-18-13(17)11-6-5-10(15)9-12(11)14;/h5-6,9H,3-4,7-8,15H2,1-2H3;1H; Key:SZKQYDBPUCZLRX-UHFFFAOYSA-N;
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Chloroprocaine, sold under the brand name Nesacaine among others is a local anesthetic given by injection.^[2] It is used as the hydrochloride salt.^[4] Chloroprocaine is a local anesthetic.^[2]^[4]

^ "Regulatory Decision Summary for Clorotekal". Drug and Health Products Portal. 22 August 2024. Retrieved 27 December 2024.
^ ^a ^b ^c "Nesacaine- chloroprocaine hydrochloride injection, solution; Nesacaine MPF- chloroprocaine hydrochloride injection, solution". DailyMed. 1 September 2022. Retrieved 21 January 2023.
^ Cite error: The named reference Iheezo FDA label was invoked but never defined (see the help page).
^ ^a ^b ^c "Clorotekal- chloroprocaine hydrochloride injection, solution". DailyMed. 4 December 2020. Retrieved 27 December 2024.
^ https://www.ema.europa.eu/en/documents/psusa/chloroprocaine-hydrochloride-list-nationally-authorised-medicinal-products-psusa00010078202203_en.pdf

[Clorotekal_CA_RDS-1] "Regulatory Decision Summary for Clorotekal". Drug and Health Products Portal. 22 August 2024. Retrieved 27 December 2024.

[Nesacaine_FDA_label-2] "Nesacaine- chloroprocaine hydrochloride injection, solution; Nesacaine MPF- chloroprocaine hydrochloride injection, solution". DailyMed. 1 September 2022. Retrieved 21 January 2023.

[Iheezo_FDA_label-3] Cite error: The named reference Iheezo FDA label was invoked but never defined (see the help page).

[Clorotekal_FDA_label-4] "Clorotekal- chloroprocaine hydrochloride injection, solution". DailyMed. 4 December 2020. Retrieved 27 December 2024.

[5] ttps://www.ema.europa.eu/en/documents/psusa/chloroprocaine-hydrochloride-list-nationally-authorised-medicinal-products-psusa00010078202203_en.pdf

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