Chondroblastoma

Chondroblastoma
Micrograph of a chondroblastoma. H&E stain.
SpecialtyOncology 

Chondroblastoma is a rare, benign, locally aggressive bone tumor that typically affects the epiphyses or apophyses of long bones.[1][2] It is thought to arise from an outgrowth of immature cartilage cells (chondroblasts) from secondary ossification centers, originating from the epiphyseal plate or some remnant of it.[2][3]

Chondroblastoma is very uncommon, accounting less than 1% of all bone tumors. (The chances of having this condition are roughly one in a million.)[1][3] It affects mostly children and young adults with most patients being less than 20 years of age.[1][4] Chondroblastoma shows a predilection towards the male sex, with a ratio of male to female patients of 2:1.[1][4][5] The most commonly affected site is the femur, followed by the humerus and tibia.[1][3][4][6] Less commonly affected sites include the talus and calcaneus of the foot and flat bones.[1][6]

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