Clesrovimab

Clesrovimab
Monoclonal antibody
TypeWhole antibody
SourceHuman
TargetRespiratory syncytial virus F protein
Clinical data
Trade namesEnflonsia
Other namesMK-1654, clesrovimab-cfor
AHFS/Drugs.comEnflonsia
License data
Routes of
administration
Intramuscular
Drug classAntiviral
ATC code
  • None
Legal status
Legal status
Identifiers
CAS Number
DrugBank
UNII
KEGG
Chemical and physical data
FormulaC6526H10118N1732O2039S40
Molar mass146747.22 g·mol−1

Clesrovimab, sold under the brand name Enflonsia, is a fully human immunoglobulin G1 kappa monoclonal antibody designed to prevent respiratory syncytial virus (RSV) infection.[1] It is a respiratory syncytial virus (RSV) F protein-directed fusion inhibitor.[1] It was developed by Merck,[2] and was approved for medical use in the United States in June 2025.[3]

  1. ^ a b c "Enflonsia- clesrovimab injection, solution". DailyMed. 20 June 2025. Retrieved 6 July 2025.
  2. ^ Cite error: The named reference Merck PR 20250609 was invoked but never defined (see the help page).
  3. ^ "Novel Drug Approvals for 2025". U.S. Food and Drug Administration (FDA). 9 June 2025. Archived from the original on 3 March 2025. Retrieved 14 June 2025.