Cocaine-induced midline destructive lesions

Cocaine-induced midline destructive lesions
SpecialtyRhinology
CausesCocaine insufflation
TreatmentSurgery
Frequency5% of cocaine users

Cocaine-induced midline destructive lesions (CIMDL)[1] is the progressive destruction of nasal architecture with the erosion of the palate, nasal conchae, and ethmoid sinuses associated with prolonged insufflation, colloquially 'snorting', of cocaine.[2] The condition begins with erosion of mucosal lining and progress with damage to nasal cartilaginous and bony structures.[1]

  1. ^ a b Nitro, Letizia; Pipolo, Carlotta; Fadda, Gian Luca; Allevi, Fabiana; Borgione, Mario; Cavallo, Giovanni; Felisati, Giovanni; Saibene, Alberto Maria (2022-07-01). "Distribution of cocaine-induced midline destructive lesions: systematic review and classification". European Archives of Oto-Rhino-Laryngology. 279 (7): 3257–3267. doi:10.1007/s00405-022-07290-1. ISSN 1434-4726. PMC 9130192. PMID 35138441.
  2. ^ Di Cosola, Michele; Ambrosino, Mariateresa; Limongelli, Luisa; Favia, Gianfranco; Santarelli, Andrea; Cortelazzi, Roberto; Lo Muzio, Lorenzo (2021-07-23). "Cocaine-Induced Midline Destructive Lesions (CIMDL): A Real Challenge in Diagnosis". International Journal of Environmental Research and Public Health. 18 (15): 7831. doi:10.3390/ijerph18157831. ISSN 1660-4601. PMC 8345435. PMID 34360121.