Colesevelam

Colesevelam
Clinical data
Trade namesWelchol, Cholestagel
AHFS/Drugs.comMonograph
MedlinePlusa699050
License data
Routes of
administration		By mouth
ATC code
Legal status
Legal status
Pharmacokinetic data
BioavailabilityN/A
MetabolismColesevelam is not absorbed and not metabolized
Elimination half-lifeN/A (non-systemic drug)
ExcretionBy intestines only, colesevelam is non-systemic
Identifiers
IUPAC name
  • Allylamine polymer with 1-chloro-2,3-epoxypropane, [6-(allylamino)-hexyl]trimethylammonium chloride and N-allyldecylamine, hydrochloride
CAS Number
PubChem CID
DrugBank
ChemSpider
  • none
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC31H67Cl3N4O
Molar mass618.25 g·mol−1
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Colesevelam is a bile acid sequestrant administered orally. It was developed by GelTex Pharmaceuticals and later acquired by Genzyme. It is marketed in the US by Daiichi Sankyo under the brand name Welchol and elsewhere by Genzyme as Cholestagel. In Canada, it is marketed by Valeant as Lodalis.

  1. ^ "Welchol- colesevelam hydrochloride tablet, film coated; Welchol- colesevelam hydrochloride for suspension". DailyMed. 7 September 2022. Archived from the original on 3 February 2023. Retrieved 16 August 2024.
  2. ^ "Welchol- colesevelam hydrochloride tablet, film coated; Welchol- colesevelam hydrochloride for suspension; Welchol- colesevelam hydrochloride bar, chewable". DailyMed. 10 June 2022. Archived from the original on 20 May 2024. Retrieved 16 August 2024.
  3. ^ "Cholestagel EPAR". European Medicines Agency (EMA). 10 March 2004. Archived from the original on 15 April 2021. Retrieved 16 August 2024.
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