Corneal ulcer

Corneal ulcer
Other namesUlcerative keratitis
Corneal ulcer resulting from bacterial keratitis
SpecialtyOphthalmology
SymptomsPain, photophobia, blurry vision
ComplicationsScarring, vision loss, uveitis, glaucoma, cataract formation
CausesBacterial, fungal, viral, or protozoal infection; immune disorders (rheumatoid arthritis, systemic sclerosis [scleroderma], rosacea)
PreventionProper contact lens hygiene
TreatmentAntibiotic, antifungal or antiviral eye drops
PrognosisGood with prompt treatment

Corneal ulcer, often resulting from keratitis is an inflammatory or, more seriously, infective condition of the cornea involving disruption of its epithelial layer with involvement of the corneal stroma.[1][2][3] It is a common condition in humans particularly in the tropics and in farming.[4] In developing countries, children afflicted by vitamin A deficiency are at high risk for corneal ulcer and may become blind in both eyes persisting throughout life. In ophthalmology, a corneal ulcer usually refers to having an infection,[2] while the term corneal abrasion refers more to a scratch injury.[5]

  1. ^ Cabrera-Aguas M, Khoo P, Watson SL (July 2022). "Infectious keratitis: A review". Clinical and Experimental Ophthalmology. 50 (5): 543–562. doi:10.1111/ceo.14113. PMC 9542356. PMID 35610943.
  2. ^ a b "Corneal ulcer". Cleveland Clinic. 8 March 2022. Retrieved 6 February 2023.
  3. ^ David Turbert (13 October 2022). "What is corneal ulcer (keratitis)?". American Academy of Ophthalmology. Retrieved 6 February 2023.
  4. ^ Ung L, Bispo PJ, Shanbhag SS, Gilmore MS, Chodosh J (2019). "The persistent dilemma of microbial keratitis: Global burden, diagnosis, and antimicrobial resistance". Survey of Ophthalmology. 64 (3): 255–271. doi:10.1016/j.survophthal.2018.12.003. PMC 7021355. PMID 30590103.
  5. ^ "Corneal abrasion (scratch): First aid". Mayo Clinic. 12 August 2022. Retrieved 6 February 2023.