Craniopharyngioma

Pituicytoma
Very low magnification micrograph of an adamantinomatous craniopharyngioma. HPS stain.
SpecialtyOncology 

A craniopharyngioma is a rare type of brain tumor derived from pituitary gland embryonic tissue[1] that occurs most commonly in children, but also affects adults. It may present at any age, even in the prenatal and neonatal periods, but peak incidence rates are childhood-onset at 5–14 years and adult-onset at 50–74 years.[2] People may present with bitemporal inferior quadrantanopia leading to bitemporal hemianopsia, as the tumor may compress the optic chiasm. It has a point prevalence around two per 1,000,000.[3] Craniopharyngiomas are distinct from Rathke's cleft tumours and intrasellar arachnoid cysts.[4]

  1. ^ "Craniopharyngioma". The Lecturio Medical Concept Library. Retrieved 10 July 2021.
  2. ^ Müller HL (June 2014). "Craniopharyngioma". Endocrine Reviews. 35 (3): 513–43. doi:10.1210/er.2013-1115. PMID 24467716.
  3. ^ Garnett MR, Puget S, Grill J, Sainte-Rose C (April 2007). "Craniopharyngioma". Orphanet Journal of Rare Diseases. 2: 18. doi:10.1186/1750-1172-2-18. PMC 1855047. PMID 17425791.
  4. ^ Shin JL, Asa SL, Woodhouse LJ, Smyth HS, Ezzat S (November 1999). "Cystic lesions of the pituitary: clinicopathological features distinguishing craniopharyngioma, Rathke's cleft cyst, and arachnoid cyst". The Journal of Clinical Endocrinology and Metabolism. 84 (11): 3972–82. doi:10.1210/jcem.84.11.6114. PMID 10566636.