Döhle bodies

Döhle bodies are light blue-gray, oval, basophilic, leukocyte inclusions located in the peripheral cytoplasm of neutrophils. They measure 1–3 μm in diameter. Not much is known about their formation, but they are thought to be remnants of the rough endoplasmic reticulum.

They are named after German pathologist, Karl Gottfried Paul Döhle (1855–1928).[1][2] They are often present in conjunction with toxic granulation.[3] However, it has been found that certain healthy individuals may have persistent Döhle bodies found in neutrophils.[4]

  1. ^ synd/114 at Whonamedit?
  2. ^ K. G. P. Döhle. Vorläufige Mittheilung über Blutbefunde bei Masern. Zentralblatt für allgemeine Pathologie und pathologische Anatomie, Jena, 1892, 3: 150-152.
  3. ^ "Döhle body". Retrieved 2009-02-10.
  4. ^ Easton, J. A. (7 Jul 2008). "The Incidence of Döhle Bodies in Various Diseases and their Association with Thrombocytopenia". British Journal of Haematology. 12 (1): 54–60. doi:10.1111/j.1365-2141.1966.tb00126.x. PMID 5906269. S2CID 11400805.
This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.