Desoxypipradrol

Desoxypipradrol
Clinical data
Routes of
administration		By mouth, nasal and sublingual
ATC code
  • none
Legal status
Legal status
  • DE: Anlage II (Authorized trade only, not prescriptible)
  • UK: Class B
Pharmacokinetic data
Bioavailability>90%
MetabolismLiver
Elimination half-life16–20 hours
Identifiers
IUPAC name
  • (RS)-2-benzhydrylpiperidine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.007.525
Chemical and physical data
FormulaC18H21N
Molar mass251.373 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
SMILES
  • C1(C(C2NCCCC2)C3=CC=CC=C3)=CC=CC=C1
InChI
  • InChI=1S/C18H21N/c1-3-9-15(10-4-1)18(16-11-5-2-6-12-16)17-13-7-8-14-19-17/h1-6,9-12,17-19H,7-8,13-14H2 Y
  • Key:RWTNXJXZVGHMGI-UHFFFAOYSA-N Y
  (verify)

Desoxypipradrol, also known as 2-⁠diphenylmethylpiperidine (2-DPMP), is a drug developed by Ciba in the 1950s[1] which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI).[2]

  1. ^ US Patent 2820038 - 2-Diphenyl-Methyl-Piperidine
  2. ^ Ferris RM, Tang FL (September 1979). "Comparison of the effects of the isomers of amphetamine, methylphenidate and deoxypipradrol on the uptake of l-[3H]norepinephrine and [3H]dopamine by synaptic vesicles from rat whole brain, striatum and hypothalamus". The Journal of Pharmacology and Experimental Therapeutics. 210 (3): 422–8. PMID 39160.
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