Dopamine agonist
| Dopamine agonist | |
|---|---|
| Drug class | |
The skeletal structure of dopamine | |
| Class identifiers | |
| Use | Parkinson's disease, hyperprolactinemia, restless legs syndrome |
| ATC code | N04BC |
| Biological target | Dopamine receptors |
| External links | |
| MeSH | D010300 |
| Legal status | |
| In Wikidata | |
A dopamine agonist is a compound that activates dopamine receptors. There are two families of dopamine receptors, D1-like and D2-like. They are all G protein-coupled receptors. D1- and D5-receptors belong to the D1-like family and the D2-like family includes D2, D3 and D4 receptors.[1] Dopamine agonists are primarily used in the treatment of the motor symptoms of Parkinson's disease, and to a lesser extent, in hyperprolactinemia and restless legs syndrome.[2][3] They are also used off-label in the treatment of clinical depression. Impulse control disorders are associated with the use of dopamine agonists.[3]
- ^ Cite error: The named reference
:1was invoked but never defined (see the help page). - ^ Cite error: The named reference
:5was invoked but never defined (see the help page). - ^ a b Spencer H, Anderton RS (2024). "Trait Impulsivity as a Feature of Parkinson's Disease Treatment and Progression". Parkinsons Dis. 2024: 8770997. doi:10.1155/2024/8770997. PMC 11102119. PMID 38766569.