Econazole

Econazole
Clinical data
Trade namesSpectazole, Ecostatin, others
AHFS/Drugs.comMonograph
MedlinePlusa684049
License data
Pregnancy
category
Routes of
administration		Topical
ATC code
Legal status
Legal status
Identifiers
IUPAC name
  • (RS)-1-{2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.043.932
Chemical and physical data
FormulaC18H15Cl3N2O
Molar mass381.68 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
SMILES
  • Clc1ccc(c(Cl)c1)C(OCc2ccc(Cl)cc2)Cn3ccnc3
InChI
  • InChI=1S/C18H15Cl3N2O/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21/h1-9,12,18H,10-11H2 Y
  • Key:LEZWWPYKPKIXLL-UHFFFAOYSA-N Y
  (verify)

Econazole is an antifungal medication of the imidazole class.[3]

It was patented in 1968, and approved for medical use in 1974.[4]

  1. ^ "Econazole topical Use During Pregnancy". Drugs.com. 3 September 2018. Retrieved 31 January 2020.
  2. ^ "Spectazole (econazole nitrate 1%) Cream". DailyMed. U.S. National Library of Medicine. 30 September 2013. Retrieved 31 July 2021.
  3. ^ Thienpont D, Van Cutsem J, Van Nueten JM, Niemegeers CJ, Marsboom R (February 1975). "Biological and toxicological properties of econazole, a broad-spectrum antimycotic". Arzneimittel-Forschung. 25 (2): 224–230. PMID 1173036.
  4. ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 502. ISBN 9783527607495.
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