Edinger–Westphal nucleus
| Edinger–Westphal nucleus | |
|---|---|
Section through superior colliculus (unlabeled) showing path of oculomotor nerve. | |
Figure showing the different groups of cells, which constitute, according to Perlia, the nucleus of origin of the oculomotor nerve. 1. Posterior dorsal nucleus. 1’. Posterior ventral nucleus. 2. Anterior dorsal nucleus. 2’. Anterior ventral nucleus. 3. Central nucleus. 4. Nucleus of Edinger and Westphal. 5. Antero-internal nucleus. 6. Antero-external nucleus. 8. Crossed fibers. 9. Trochlear nerve, with 9’, its nucleus of origin, and 9", its decussation. 10. Third ventricle. M, M. Median line. | |
| Details | |
| Parts | Provides input to parasympathetic root of ciliary ganglion |
| Identifiers | |
| Latin | nuclei accessorii nervi oculomotorii |
| MeSH | D065839 |
| NeuroNames | 498 |
| NeuroLex ID | birnlex_822 |
| Anatomical terms of neuroanatomy | |
The Edinger–Westphal nucleus also called the accessory or visceral oculomotor nerve, is one of the two nuclei of the oculomotor nerve (CN III) located in the midbrain.[1][2][3] It receives afferents from both pretectal nuclei (which have in turn received afferents from the optic tract).[4] It contains parasympathetic pre-ganglionic neuron cell bodies that synapse in the ciliary ganglion.[3][2] It contributes the autonomic, parasympathetic component to the oculomotor nerve (CN III),[4] ultimately providing innervation to the iris sphincter muscle and ciliary muscle to mediate the pupillary light reflex and accommodation, respectively.[2][3]
The Edinger–Westphal nucleus has two parts. The first is of preganglionic fibers (EWpg) that terminate in the ciliary ganglion. The second is of centrally projecting cells (EWcp) that project to a number of brainstem structures.[5][3][6]
- ^ Joyce, Christopher; Le, Patrick H.; Peterson, Diana C. (2022), "Neuroanatomy, Cranial Nerve 3 (Oculomotor)", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 30725811, retrieved 2022-08-08
- ^ a b c Sonne, James; Lopez-Ojeda, Wilfredo (2022), "Neuroanatomy, Cranial Nerve", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 29261885, retrieved 2022-08-08
- ^ a b c d Heiland Hogan, Madeline B.; Subramanian, Suriya; M Das, Joe (2022), "Neuroanatomy, Edinger–Westphal Nucleus (Accessory Oculomotor Nucleus)", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 32119442, retrieved 2022-08-08
- ^ a b Yoo, Hannah; Mihaila, Dana M. (2023), "Neuroanatomy, Pupillary Light Reflexes and Pathway", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 31985962, retrieved 2023-08-15
- ^ Haines, Duane (2018). Fundamental neuroscience for basic and clinical applications (Fifth ed.). Philadelphia, PA: Elsevier. p. 188. ISBN 9780323396325.
- ^ Kozicz T, Bittencourt JC, May PJ, Reiner A, Gamlin PD, Palkovits M, Horn AK, Toledo CA, Ryabinin AE (2011). "The Edinger–Westphal nucleus: A historical, structural and functional perspective on a dichotomous terminology". J. Comp. Neurol. 519 (8): 1413–34. doi:10.1002/cne.22580. PMC 3675228. PMID 21452224.