Electronic cigarette

An electronic cigarette (e-cigarette), or vape,[note 1][1] is a device that simulates tobacco smoking. It consists of an atomizer, a power source such as a battery, and a container such as a cartridge or tank. Instead of smoke, the user inhales vapor,[2] often called "vaping".[3]

The atomizer is a heating element that vaporizes a liquid solution called e-liquid[4] that cools into an aerosol of tiny droplets, vapor and air.[5] The vapor mainly comprises propylene glycol and/or glycerin, usually with nicotine and flavoring. Its exact composition varies, and depends on matters such as user behavior.[note 2] E-cigarettes are activated by taking a puff or pressing a button.[3][6] Some look like traditional cigarettes,[3][7] and most kinds are reusable.[note 3]

Vaping is less harmful than smoking,[9] but still has health risks.[10] Vaping affects asthma[11] and chronic obstructive pulmonary disease.[12][13][14] Nicotine is highly addictive.[15] Limited evidence indicates that e-cigarettes are less addictive than smoking, with slower nicotine absorption rates.[16][17]

E-cigarettes containing nicotine are more effective than nicotine replacement therapy (NRT) for smoking cessation,[18] but have not been subject to the same rigorous testing that most nicotine replacement therapy products have.[19]

  1. ^ a b "Vaporizers, E-Cigarettes, and other Electronic Nicotine Delivery Systems (ENDS)". United States Food and Drug Administration. 14 February 2020. Archived from the original on 29 April 2019. This article incorporates text from this source, which is in the public domain.
  2. ^ a b Cheng, T. (2014). "Chemical evaluation of electronic cigarettes". Tobacco Control. 23 (Supplement 2): ii11 – ii17. doi:10.1136/tobaccocontrol-2013-051482. ISSN 0964-4563. PMC 3995255. PMID 24732157.
  3. ^ a b c Orellana-Barrios, Menfil A.; Payne, Drew; Mulkey, Zachary; Nugent, Kenneth (2015). "Electronic cigarettes-a narrative review for clinicians". The American Journal of Medicine. 128 (7): 674–81. doi:10.1016/j.amjmed.2015.01.033. ISSN 0002-9343. PMID 25731134.
  4. ^ Weaver, Michael; Breland, Alison; Spindle, Tory; Eissenberg, Thomas (2014). "Electronic Cigarettes". Journal of Addiction Medicine. 8 (4): 234–240. doi:10.1097/ADM.0000000000000043. ISSN 1932-0620. PMC 4123220. PMID 25089953.
  5. ^ David, Grégory; Parmentier, Evelyne A.; Taurino, Irene; Signorell, Ruth (December 2020). "Tracing the composition of single e-cigarette aerosol droplets in situ by laser-trapping and Raman scattering". Scientific Reports. 10 (1): 7929. Bibcode:2020NatSR..10.7929D. doi:10.1038/s41598-020-64886-5. PMC 7220912. PMID 32404884.
  6. ^ Cite error: The named reference Rahman2014 was invoked but never defined (see the help page).
  7. ^ Pepper, J. K.; Brewer, N. T. (2013). "Electronic nicotine delivery system (electronic cigarette) awareness, use, reactions and beliefs: a systematic review". Tobacco Control. 23 (5): 375–384. doi:10.1136/tobaccocontrol-2013-051122. ISSN 0964-4563. PMC 4520227. PMID 24259045.
  8. ^ Drope, Jeffrey; Cahn, Zachary; Kennedy, Rosemary; Liber, Alex C.; Stoklosa, Michal; Henson, Rosemarie; Douglas, Clifford E.; Drope, Jacqui (November 2017). "Key issues surrounding the health impacts of electronic nicotine delivery systems (ENDS) and other sources of nicotine". CA: A Cancer Journal for Clinicians. 67 (6): 449–471. doi:10.3322/caac.21413. ISSN 0007-9235. PMID 28961314. S2CID 32928770.
  9. ^ Yayan, Josef; Franke, Karl-Josef; Biancosino, Christian; Rasche, Kurt (1 March 2024). "Comparative systematic review on the safety of e-cigarettes and conventional cigarettes". Food and Chemical Toxicology. 185 114507. doi:10.1016/j.fct.2024.114507. ISSN 0278-6915. PMID 38331086.
  10. ^ Balfour, David J. K.; Benowitz, Neal L.; Colby, Suzanne M.; Hatsukami, Dorothy K.; Lando, Harry A.; Leischow, Scott J.; Lerman, Caryn; Mermelstein, Robin J.; Niaura, Raymond; Perkins, Kenneth A.; Pomerleau, Ovide F.; Rigotti, Nancy A.; Swan, Gary E.; Warner, Kenneth E.; West, Robert (September 2021). "Balancing Consideration of the Risks and Benefits of E-Cigarettes". American Journal of Public Health. 111 (9): 1661–1672. doi:10.2105/AJPH.2021.306416. PMC 8589069. PMID 34410826. Among potentially toxic substances common to both products, cigarette smoke generally contains substantially larger quantities than e-cigarette aerosol. However, e-cigarette aerosol contains some substances not found in cigarette smoke."
  11. ^ Chand, Benjamin R.; and Hosseinzadeh, Hassan (2 September 2022). "Association between e-cigarette use and asthma: a systematic review and meta-analysis". Journal of Asthma. 59 (9): 1722–1731. doi:10.1080/02770903.2021.1971703. ISSN 0277-0903. PMID 34433366.
  12. ^ Song, Chunyan; Hao, Xiaoning; Critselis, Elena; Panagiotakos, Demosthenes (1 April 2025). "The impact of electronic cigarette use on chronic obstructive pulmonary disease: A systematic review and meta-analysis". Respiratory Medicine. 239 107985. doi:10.1016/j.rmed.2025.107985. ISSN 0954-6111. PMID 39921069.
  13. ^ Erhabor, John; Yao, Zhiqi; Tasdighi, Erfan; Benjamin, Emelia J.; Bhatnagar, Aruni; Blaha, Michael J. (2025). "E-cigarette Use and Incident Cardiometabolic Conditions in the All of Us Research Program". Nicotine & Tobacco Research ntaf067. doi:10.1093/ntr/ntaf067. PMID 40089810.
  14. ^ Caci, Grazia; Selya, Arielle; La Rosa, Giusy Rita Maria; Spicuzza, Lucia; Morjaria, Jaymin B.; Geraci, Giulio; Polosa, Riccardo (1 March 2025). "Respiratory effects of electronic cigarette use in individuals who never smoked: A systematic review". Clinical Medicine. 25 (2): 100295. doi:10.1016/j.clinme.2025.100295. ISSN 1470-2118. PMC 11930579. PMID 39993529.
  15. ^ "Policy on Electronic Nicotine Delivery Systems (ENDS)" (PDF). American Academy of Pediatrics. 2020. Retrieved 13 November 2022.
  16. ^ National Academies of Sciences, Engineering, and Medicine (NASEM) (18 May 2018). Stratton, Kathleen; Kwan, Leslie Y.; Eaton, David L. (eds.). "Public Health Consequences of E-Cigarettes". National Academies Press. National Academies Press (US). doi:10.17226/24952. ISBN 978-0-309-46834-3. PMID 29894118.{{cite journal}}: CS1 maint: multiple names: authors list (link) |quote="There is moderate evidence that risk and severity of dependence are lower for e-cigarettes than combustible tobacco cigarettes."
  17. ^ UK Office for Health Improvement and Disparities (OHID) (2022). "Nicotine vaping in England: an evidence update including health risks and perceptions, September 2022. A report commissioned by the Office for Health Improvement and Disparities" (PDF). Uk.gov. Retrieved 27 December 2024.|quote=...there is substantial evidence that vaping product use delivers lower peak and overall nicotine levels to users than smoking, which may translate to lower dependence risks compared with smoking.
  18. ^ Lindson, Nicola; Butler, Ailsa R.; McRobbie, Hayden; Bullen, Chris; Hajek, Peter; Wu, Angela Difeng; Begh, Rachna; Theodoulou, Annika; Notley, Caitlin; Rigotti, Nancy A.; Turner, Tari; Livingstone-Banks, Jonathan; Morris, Tom; Hartmann-Boyce, Jamie (29 January 2025). "Electronic cigarettes for smoking cessation". The Cochrane Database of Systematic Reviews. 1 (1): CD010216. doi:10.1002/14651858.CD010216.pub9. ISSN 1469-493X. PMC 11776059. PMID 39878158.
  19. ^ Carpenter, Matthew J.; Wahlquist, Amy E.; Dahne, Jennifer; Gray, Kevin M.; Cummings, K. Michael; Warren, Graham; Wagener, Theodore L.; Goniewicz, Maciej L.; Smith, Tracy T. (September 2023). ""Effect of unguided e-cigarette provision on uptake, use, and smoking cessation among adults who smoke in the USA: a naturalistic, randomised, controlled clinical trial."". eClinicalMedicine. 63 102142. doi:10.1016/j.eclinm.2023.102142. PMC 10518503. PMID 37753443.


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