Endolymphatic sac
| Endolymphatic sac | |
|---|---|
Endolymphatic sac appears as #6 in Fig 4 | |
| Details | |
| Identifiers | |
| Latin | saccus endolymphaticus |
| MeSH | D004712 |
| TA98 | A15.3.03.080 |
| TA2 | 7007 |
| FMA | 75639 |
| Anatomical terminology | |
In anatomy, the endolymphatic sac is a structure in the inner ear. It is a dead end pouch located at the end of the endolymphatic duct, on the posterior surface of the petrous portion of the temporal bone, where it is in contact with the dura mater.
Studies suggest that the endolymphatic duct and endolymphatic sac perform functions absorptive, secretory,[1][2][3][4] phagocytic,[5] and immunodefensive.[6] Supporting evidence:
- contrast agent uptake in the endolymphatic sac and duct in MRI is inversely correlated to endolymphatic hydrops,[7]
- endolymphatic sac and duct morphology changes have been observed in Meniere's Disease.[8]
Neoplasms of the endolymphatic sac are very rare tumors.
- ^ Schuknecht HF. Pathology of the Ear. Philadelphia, Pa: Lea & Febiger; 1993:45–47, 50–51, 62, 64, 101
- ^ Wackym, P. A.; Friberg, U.; Bagger-Sjöbäck, D.; Linthicum, F. H.; Friedmann, I.; Rask-Andersen, H. (August 1987). "Human endolymphatic sac: possible mechanisms of pressure regulation". The Journal of Laryngology and Otology. 101 (8): 768–779. doi:10.1017/s0022215100102713. ISSN 0022-2151. PMID 3655528.
- ^ Yeo, S. W.; Gottschlich, S.; Harris, J. P.; Keithley, E. M. (June 1995). "Antigen diffusion from the perilymphatic space of the cochlea". The Laryngoscope. 105 (6): 623–628. doi:10.1288/00005537-199506000-00012. ISSN 0023-852X. PMID 7769947.
- ^ Rask-Andersen, H.; Danckwardt-Lillieström, N.; Linthicum, F. H.; House, W. F. (February 1991). "Ultrastructural evidence of a merocrine secretion in the human endolymphatic sac". The Annals of Otology, Rhinology, and Laryngology. 100 (2): 148–156. doi:10.1177/000348949110000211. ISSN 0003-4894. PMID 1992902.
- ^ Fukazawa, K.; Sakagami, M.; Matsunaga, T.; Fujita, H. (July 1991). "Endocytotic activity of the free floating cells and epithelial cells in the endolymphatic sac: an electron microscopic study". The Anatomical Record. 230 (3): 425–433. doi:10.1002/ar.1092300315. ISSN 0003-276X. PMID 1867416.
- ^ Wackym, P. A.; Friberg, U.; Linthicum, F. H.; Bagger-Sjöbäck, D.; Bui, H. T.; Hofman, F.; Rask-Andersen, H. (May–June 1987). "Human endolymphatic sac: morphologic evidence of immunologic function". The Annals of Otology, Rhinology, and Laryngology. 96 (3 Pt 1): 276–281. doi:10.1177/000348948709600308. ISSN 0003-4894. PMID 3300505.
- ^ J. Gerb, E. Kierig, V. Kirsch, Sandra Becker‐Bense, Rainer Boegle, Thomas Brandt, Marianne Dieterich: Contrast Agent Uptake in Endolymphatic Sac and Duct: Inverse Relation to Endolymphatic Hydrops. In: The Laryngoscope. 2025 doi:10.1002/lary.32127.
- ^ David Bächinger, Ngoc-Nhi Luu, Judith Kempfle, Samuel R. Barber, Daniel Zürrer, Daniel J. Lee, Hugh D. Curtin, Steven D. Rauch, Joseph B. Nadol, Joe C. Adams, Andreas H. Eckhard: Vestibular Aqueduct Morphology Correlates With Endolymphatic Sac Pathologies in Menière's Disease—A Correlative Histology and Computed Tomography Study. In: Otology & Neurotology. 2019, Band 40, Nummer 5, S. e548–e555 doi:10.1097/MAO.0000000000002198.