Epratuzumab
| Monoclonal antibody | |
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| Type | Whole antibody |
| Source | Humanized (from mouse) |
| Target | CD22 |
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| Trade names | LymphoCide |
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Epratuzumab (planned trade name LymphoCide) is a humanized monoclonal antibody. Potential uses may be found in oncology and in treatment of inflammatory autoimmune disorders, such as systemic lupus erythematosus (SLE).[1][2]
- ^ Carnahan J, Wang P, Kendall R, Chen C, Hu S, Boone T, et al. (September 2003). "Epratuzumab, a humanized monoclonal antibody targeting CD22: characterization of in vitro properties". Clinical Cancer Research. 9 (10 Pt 2): 3982S – 90S. PMID 14506197.
- ^ Lindén O, Hindorf C, Cavallin-Ståhl E, Wegener WA, Goldenberg DM, Horne H, et al. (July 2005). "Dose-fractionated radioimmunotherapy in non-Hodgkin's lymphoma using DOTA-conjugated, 90Y-radiolabeled, humanized anti-CD22 monoclonal antibody, epratuzumab". Clinical Cancer Research. 11 (14): 5215–22. doi:10.1158/1078-0432.CCR-05-0172. PMID 16033839.